Nolte C H, Audebert H J
Center for Stroke Research Berlin, Charité - Universitätsmedizin Berlin, Hindenburgdamm 30, 12203, Berlin, Deutschland.
Klinik und Hochschulambulanz für Neurologie, Charité Campus Benjamin Franklin, Hindenburgdamm 30, 12203, Berlin, Deutschland.
Med Klin Intensivmed Notfmed. 2017 Nov;112(8):668-673. doi: 10.1007/s00063-017-0348-z. Epub 2017 Sep 12.
The effectiveness of thrombolysis or mechanical recanalization for acute stroke is higher, the sooner these therapies are started. Therefore, acute stroke patients need to be evaluated by qualified staff for these therapies as soon as possible. Lay persons need to identify the typical symptoms of stroke as an emergency and act accordingly by calling the emergency medical system (EMS). The EMS team reassesses the symptoms and prompts cerebral imaging. Cerebral imaging is performed ideally in hospitals with a stroke unit where subsequent (stroke) treatments occur. On the way, the emergency team will measure and stabilize vital functions and obtain further important clinical information. Telemedicine allows communicating exact time of onset and severity of symptoms, as well as comorbidities and medication of the patient to the respective hospital. Thereby, the intrahospital workload will be disencumbered and accelerated. Some EMS vehicles now carry point-of-care laboratories and may measure lab values en route (glucose and INR [International Normalized Ratio] for example). Some ambulances are not only equipped with qualified staff, telemedicine technique, and point-of-care labs but even computer tomography (CT) to perform imaging. Such mobile stroke emergency mobiles (STEMO) or mobile stroke units may perform thrombolysis prehospitally. Prehospital thrombolysis has been proven to be initiated faster and is safe. Preliminary results even suggest superiority to intrahospital thrombolysis with respect to clinical outcome. Moreover, STEMO may perform CT-angiography and assess intracranial large-vessel status. If intracranial large-vessel occlusion is present, patients will be brought directly to hospitals able to perform mechanical recanalization. Thus, secondary transports are no longer required.
急性中风溶栓或机械再通治疗开始得越早,其有效性越高。因此,急性中风患者需要尽快由专业人员对这些治疗进行评估。非专业人员需要识别中风的典型症状作为紧急情况,并通过呼叫紧急医疗系统(EMS)采取相应行动。EMS团队会重新评估症状并促使进行脑部成像检查。理想情况下,脑部成像检查应在设有中风单元且后续会进行(中风)治疗的医院进行。在转运途中,急救团队会测量并稳定生命体征,获取更多重要的临床信息。远程医疗能够将患者症状发作的确切时间、严重程度以及合并症和用药情况传达给相应医院。由此,医院内的工作量将得到减轻并加快处理速度。现在一些EMS车辆配备了即时检验实验室,可能会在途中测量实验室指标(例如血糖和国际标准化比值[INR])。一些救护车不仅配备了专业人员、远程医疗技术和即时检验实验室,甚至还配备了计算机断层扫描(CT)用于成像检查。这种移动中风急救车(STEMO)或移动中风单元可以在院前进行溶栓治疗。院前溶栓已被证明启动更快且安全。初步结果甚至表明,在临床结局方面,院前溶栓优于院内溶栓。此外,STEMO可以进行CT血管造影并评估颅内大血管状况。如果存在颅内大血管闭塞,患者将被直接送往能够进行机械再通治疗的医院。这样就不再需要二次转运。