非甾体抗炎药、血浆半衰期及不良反应。 - Suppr

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超能文献

Non-steroidal anti-inflammatory drugs, plasma half-lives, and adverse reactions.

作者信息

Adams S S

出版信息

Lancet. 1987 Nov 21;2(8569):1204-5. doi: 10.1016/s0140-6736(87)91335-3.

DOI:10.1016/s0140-6736(87)91335-3

PMID:2890822

Abstract

摘要

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Non-steroidal anti-inflammatory drugs, plasma half-lives, and adverse reactions.非甾体抗炎药、血浆半衰期及不良反应。

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NSAIDs, plasma half-lives, and adverse reactions.非甾体抗炎药、血浆半衰期及不良反应。

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NSAIDs, plasma half-lives, and adverse reactions.非甾体抗炎药、血浆半衰期及不良反应。

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Ibuprofen piconol hydrolysis in vitro in plasma, whole blood, and serum using different anticoagulants.使用不同抗凝剂在体外血浆、全血和血清中进行异丁苯丙酸皮考诺酯水解实验。

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Pharmacokinetics, safety, and tolerability of a rapid infusion of i.v. ibuprofen in healthy adults.静脉注射布洛芬快速输注在健康成年人中的药代动力学、安全性和耐受性。

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Ibuprofen plasma concentration profile in deliberate ibuprofen overdose with circulatory depression treated with therapeutic plasma exchange: a case report.治疗性血浆置换治疗布洛芬蓄意过量致循环抑制时的布洛芬血浆浓度变化：1例报告

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[Pharmacokinetic variables under therapy with a nonsteroidal antirheumatic with a short half-life in patients over 65 years old].[65岁以上患者使用半衰期短的非甾体类抗风湿药治疗时的药代动力学变量]

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Ibuprofen: from invention to an OTC therapeutic mainstay.布洛芬：从发明到成为非处方药的治疗支柱。

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Exercise caution when taking ibuprofen. High doses of ibuprofen have been associated with an increased risk of cardiovascular events. How much is safe?服用布洛芬时要谨慎。高剂量布洛芬与心血管事件风险增加有关。多少剂量是安全的？

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引用本文的文献

Comparison of Clinical Effectiveness and Safety of Newer Nonsteroidal Anti-inflammatory Drugs in Patients of Osteoarthritis of Knee Joint: A Randomized, Prospective, Open-label Parallel-group Study.新型非甾体抗炎药治疗膝关节骨关节炎患者的临床有效性和安全性比较：一项随机、前瞻性、开放标签平行组研究。

Indian J Pharmacol. 2017 Sep-Oct;49(5):383-389. doi: 10.4103/ijp.IJP_245_16.

Fifty years since the discovery of ibuprofen.布洛芬发现五十周年。

Inflammopharmacology. 2011 Dec;19(6):293-7. doi: 10.1007/s10787-011-0103-7.

Influence of prolonged exposure of a short half life non-steroidal anti-inflammatory drugs on gastrointestinal safety.短半衰期非甾体抗炎药长期暴露对胃肠道安全性的影响。

Inflammopharmacology. 2009 Aug;17(4):205-10. doi: 10.1007/s10787-009-0007-y. Epub 2009 Jul 8.

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Clin Drug Investig. 2004;24(4):227-36. doi: 10.2165/00044011-200424040-00004.

Pain treatment with NSAIDs, primary focus on ibuprofen.使用非甾体抗炎药进行疼痛治疗，主要关注布洛芬。

Clin Rheumatol. 2001 Nov;20 Suppl 1:S6-8. doi: 10.1007/BF03342661.

Efficacy and long-term safety of dexibuprofen [S(+)-ibuprofen]: a short-term efficacy study in patients with osteoarthritis of the hip and a 1-year tolerability study in patients with rheumatic disorders.右旋布洛芬[S(+)-布洛芬]的疗效及长期安全性：一项针对髋骨关节炎患者的短期疗效研究及一项针对风湿性疾病患者的1年耐受性研究

Clin Rheumatol. 2001 Nov;20 Suppl 1:S22-9. doi: 10.1007/BF03342664.

Choosing the right nonsteroidal anti-inflammatory drug for the right patient: a pharmacokinetic approach.为合适的患者选择合适的非甾体抗炎药：一种药代动力学方法。

Clin Pharmacokinet. 2000 May;38(5):377-92. doi: 10.2165/00003088-200038050-00001.

Pharmacokinetic optimisation of the treatment of osteoarthritis.骨关节炎治疗的药代动力学优化

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Pharmacokinetics of the anti-inflammatory drug ximoprofen in healthy subjects and in disease states.抗炎药物西莫洛芬在健康受试者及疾病状态下的药代动力学。

Eur J Clin Pharmacol. 1991;40(1):101-6. doi: 10.1007/BF00315147.

Diclofenac delays healing of gastroduodenal mucosal lesions. Double-blind, placebo-controlled endoscopic study in healthy volunteers.双氯芬酸会延迟胃十二指肠黏膜损伤的愈合。在健康志愿者中进行的双盲、安慰剂对照内镜研究。

Dig Dis Sci. 1991 May;36(5):594-600. doi: 10.1007/BF01297025.

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