Department of Textile and Polymer Engineering, Yazd Branch, Islamic Azad University, Yazd, Iran.
Scientific Society of Nanotechnology, Yazd Branch, Islamic Azad University, Yazd, Iran.
J Food Drug Anal. 2016 Apr;24(2):406-416. doi: 10.1016/j.jfda.2015.11.011. Epub 2016 Mar 8.
In the present study, the fabrication of a new modified electrode for electrocatalytic oxidation of noradrenalin, based on the delphinidin immobilized on silver nanoparticles modified glassy carbon electrode. Cyclic voltammetry was used to investigate the redox properties of this modified electrode. The surface charge transfer rate constant (k) and the charge transfer coefficient (α) for the electron transfer between the glassy carbon electrode and the immobilized delphinidin were calculated. The differential pulse voltammetry exhibited two linear dynamic ranges and a detection limit of 0.40μM for noradrenalin determination. Moreover, the present electrode could separate the oxidation peak potentials of ascorbic acid, noradrenalin, uric acid, and tryptophan in a mixture. The usefulness of this nanosensor was also investigated for the determination of ascorbic acid, noradrenalin, and uric acid in pharmaceutical and biological fluid samples with satisfactory results.
在本研究中，基于银纳米粒子修饰的矢车菊素固定在玻碳电极上，制备了一种用于去甲肾上腺素电催化氧化的新型修饰电极。循环伏安法用于研究该修饰电极的氧化还原性质。计算了玻碳电极和固定矢车菊素之间电子转移的表面电荷转移速率常数（k）和电荷转移系数（α）。差分脉冲伏安法显示出两个线性动态范围和 0.40μM 的去甲肾上腺素检测限。此外，该电极可以在混合物中分离抗坏血酸、去甲肾上腺素、尿酸和色氨酸的氧化峰电位。该纳米传感器还用于测定药物和生物流体样品中的抗坏血酸、去甲肾上腺素和尿酸，结果令人满意。
