Gheorghiu Gabriel, Benteu Diana, Neamţu Claudiu, Boieru Raluca, Ţăranu Georgel, Săndesc Dorel
"Victor Babes" University of Medicine and Pharmacy Timisoara, X Department, Intensive Care Department, Romania.
Emergency County Hospital Timisoara, Intensive Care Department, Romania.
Rom J Anaesth Intensive Care. 2015 Apr;22(1):55-58.
The intraoperative vs postoperative initiation of haemofiltration procedures in patients submitted for major vascular surgery is a controversial issue and a subject of debate in recent literature. We report the case of a 50 yr old patient scheduled for aorto-bifemoral bypass with mesenteric revascularization in whom the haemofiltration procedure (Prismaflex with Onix filter) was installed intraoperatively. Known to have non-insulin-dependent type 2 diabetes, the patient was admitted for Leriche syndrome, abdominal aorta thrombosis, superior and inferior mesenteric artery occlusion, celiac trunk occlusion, bilateral critical limb ischemia and mild renal impairment. The filtration rate was 25 ml/kg/h, ultrafiltration rate of 50 ml/h and 2 h clampation time. Haemofiltration was continued postoperatively in the ICU for another 48 h. The patient had a favorable evolution with restoration of renal function and a significant improvement of the biochemical parameters. In conclusion the early haemofiltration applied in this case provided clear beneficial effects, probably preventing the evolution towards multiple organ dysfunction syndrome.
对于接受大血管手术的患者,术中还是术后开始血液滤过程序是一个有争议的问题,也是近期文献中争论的主题。我们报告一例50岁计划行主动脉-双股动脉搭桥术并肠系膜血管重建术的患者,术中安装了血液滤过程序(使用Onix滤器的Prismaflex)。该患者已知患有非胰岛素依赖型2型糖尿病,因勒里什综合征、腹主动脉血栓形成、肠系膜上动脉和下动脉闭塞、腹腔干闭塞、双侧严重肢体缺血和轻度肾功能损害入院。滤过率为25 ml/kg/h,超滤率为50 ml/h,钳夹时间为2小时。术后在重症监护病房继续进行血液滤过48小时。患者病情进展良好,肾功能恢复,生化指标显著改善。总之,本病例中应用的早期血液滤过产生了明显的有益效果,可能预防了向多器官功能障碍综合征的发展。