Department of Behavioral Science and Center on Drug and Alcohol Research, University of Kentucky, Lexington, KY (HKK, MRL, SLW, JRH); and Department of Behavioral Science, University of Kentucky, Lexington, KY (JLS).
J Addict Med. 2018 Jan/Feb;12(1):31-39. doi: 10.1097/ADM.0000000000000360.
Few studies have considered how providers make decisions to prescribe buprenorphine to new patients with opioid use disorder. This study examined the relative importance of patients' clinical, financial, and social characteristics on physicians' decision-making related to willingness to prescribe buprenorphine to new patients and the number of weeks of medication that they are willing to initially prescribe after induction.
A national sample of 1174 current prescribers was surveyed. Respondents rated willingness to prescribe on a 0 to 10 scale and indicated the number of weeks of medication (ranging from none to >4 weeks) for 20 hypothetical patients. Conjoint analysis estimated relative importance scores and part-worth utilities for these 2 outcome ratings.
The mean rating for willingness to prescribe was 5.52 (SD 2.47), indicating a moderate willingness to implement buprenorphine treatment. The mean prescription length was 2.06 (SD 1.34), which corresponds to 1 week of medication. For both ratings, the largest importance scores were for other risky substance use, method of payment, and spousal involvement in treatment. Illicit benzodiazepine use, having Medicaid insurance to pay for the office visit, and having an opioid-using spouse were negatively associated with these outcome ratings, whereas a history of no risky alcohol or benzodiazepine use, cash payment, and having an abstinent spouse were positively associated with both ratings.
Reticence to prescribe to individuals using an illicit benzodiazepine and individuals with a drug-using spouse aligns with practice guidelines. However, reluctance to prescribe to patients with Medicaid may hamper efforts to expand access to treatment.
鲜有研究关注医生在为新的阿片类药物使用障碍患者开具丁丙诺啡时的决策过程。本研究旨在考察患者的临床、财务和社会特征对医生是否愿意为新患者开具丁丙诺啡以及愿意在诱导期后最初开出多少周药物的决策的相对重要性。
对全国范围内的 1174 名现职处方者进行了调查。受访者对开具处方的意愿进行了 0 到 10 的评分,并为 20 名虚构患者表示愿意开出的药物周数(从无到>4 周)。联合分析估计了这两个结果评分的相对重要性得分和部分价值效用。
愿意开具处方的平均评分为 5.52(SD 2.47),表明实施丁丙诺啡治疗的意愿中等。平均处方长度为 2.06(SD 1.34),对应 1 周的药物治疗。对于这两个评分,最重要的评分因素是其他危险物质使用、支付方式和配偶参与治疗。非法苯二氮䓬类药物使用、使用医疗补助保险支付就诊费用以及有阿片类药物使用的配偶与这些结果评分呈负相关,而没有危险的酒精或苯二氮䓬类药物使用史、现金支付和有操守的配偶与这两个评分均呈正相关。
不愿为使用非法苯二氮䓬类药物的个体和有吸毒配偶的个体开具处方,这与实践指南一致。然而,不愿为有医疗补助的患者开具处方可能会阻碍扩大治疗的努力。