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[分流性颅骨缝早闭:问题的时效性、治疗方法的选择及手术治疗特点]

[Shunt-induced craniosynostosis: topicality of the problem, choice of the approach, and features of surgical treatment].

作者信息

Kim S A, Letyagin G V, Danilin V E, Sysoeva A A

机构信息

Federal Neurosurgical Center, Novosibirsk, Russia.

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 2017;81(4):45-55. doi: 10.17116/neiro201781445-55.

Abstract

RATIONALE

Shunt-induced craniosynostosis is one of the late complications of CSF shunting surgery, which affects the patient's condition, clinical picture, and treatment approach.

OBJECTIVE

to evaluate the prevalence rate and clinical significance of this disease, define the indications for surgery, and choose the optimal surgical approach.

MATERIAL AND METHODS

The study included 59 children with shunt system dysfunction, aged 1 to 14 years, who were treated at the Department in the period from 2014 to 2016. The inclusion criteria were as follows: 1) age at the time of examination is older than 1 year; 2) implantation of a shunt system in the first 12 months of life. The state of cranial sutures was assessed using three-dimensional reconstruction of patient's computerized tomography images. Images obtained before or in the first months after primary implantation of a shunt system were used to exclude cases of primary craniosynostosis.

RESULTS

Premature synostosis of the cranial sutures was detected in 27 (46%) cases. Of these, 3 (11%) patients with clinical symptoms of increased intracranial pressure and radiographic signs of craniocerebral disproportion underwent cranial vault remodeling surgery: two biparietal craniotomies and one fronto-parieto-occipital reconstruction. In two cases, simultaneous replacement of a valve with a programmable one was performed. There were no complications after reconstructive surgery.

CONCLUSION

Shunt-associated craniosynostosis is one of the late complications of CSF shunting surgery. However, its presence is not an indication for surgery and should not be a reason for surgical aggression. Surgery for increasing the intracranial volume is indicated only for secondary craniosynostosis combined with signs of craniocerebral disproportion. In these cases, reconstructive surgery is an effective treatment option for improving the patient's condition.

摘要

理论依据

分流性颅骨缝早闭是脑脊液分流手术的晚期并发症之一,会影响患者的病情、临床表现和治疗方法。

目的

评估该疾病的患病率和临床意义,确定手术指征,并选择最佳手术方式。

材料与方法

该研究纳入了2014年至2016年期间在该科室接受治疗的59例分流系统功能障碍患儿,年龄在1至14岁之间。纳入标准如下:1)检查时年龄大于1岁;2)在出生后的前12个月内植入分流系统。使用患者计算机断层扫描图像的三维重建来评估颅缝状态。在分流系统初次植入之前或之后的头几个月内获得的图像用于排除原发性颅骨缝早闭病例。

结果

在27例(46%)病例中检测到颅缝过早闭合。其中,3例(11%)有颅内压升高临床症状和颅脑不对称影像学表现的患者接受了颅骨重塑手术:2例双侧顶骨开颅手术和1例额顶枕重建手术。在2例病例中,同时将瓣膜更换为可编程瓣膜。重建手术后无并发症发生。

结论

分流相关性颅骨缝早闭是脑脊液分流手术的晚期并发症之一。然而,其存在并非手术指征,也不应成为激进手术的理由。仅在继发性颅骨缝早闭合并颅脑不对称体征时才考虑进行增加颅内容积的手术。在这些情况下,重建手术是改善患者病情的有效治疗选择。

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