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子宫肌瘤管理的更新方法。

Updated approaches for management of uterine fibroids.

作者信息

Mas Aymara, Tarazona Marta, Dasí Carrasco Joana, Estaca Gloria, Cristóbal Ignacio, Monleón Javier

机构信息

Reproductive Medicine Research Group, Institute of Health Research La Fe, University and Polytechnic Hospital La Fe, Valencia, Spain.

Research and Development Department, Igenomix Foundation, Valencia, Spain.

出版信息

Int J Womens Health. 2017 Sep 5;9:607-617. doi: 10.2147/IJWH.S138982. eCollection 2017.

Abstract

Uterine anatomy and uterine fibroids (UFs) characteristics have been classically considered as almost a unique issue in gynecology and reproductive medicine. Nowadays, the management of UF pathology is undergoing an important evolution, with the patient's quality of life being the most important aspect to consider. Accordingly, surgical techniques and aggressive treatments are reserved for only those cases with heavy symptomatology, while the clinical diagnostic based on size and number of UFs remains in a second plane in these situations. Moreover, the development of several noninvasive surgical techniques, especially the appearance of ulipristal acetate as a medical etiological treatment, has substantially changed the clinical indications. As a consequence, after almost 2 decades without relevant updates, it has been necessary to update the protocols for the management of UFs in the Spanish Society of Gynecology and Obstetrics twice. Accordingly, we believe that it is necessary to translate our experience to protocolize the medical care for patients with UFs, incorporating these new therapeutic options, and selecting the best treatment for them. We highlight the importance of achieving the patient's goals and decisions by improving the clinical diagnosis for these type of pathologies, allowing enhanced personalized treatments, as well as the reduction of potential risks and unnecessary surgeries.

摘要

子宫解剖结构及子宫肌瘤(UFs)特征传统上几乎被视为妇科和生殖医学中一个独特的问题。如今,子宫肌瘤病理的管理正在经历重大变革,患者的生活质量成为最重要的考量因素。因此,手术技术和积极治疗仅适用于那些症状严重的病例,而在这些情况下,基于子宫肌瘤大小和数量的临床诊断则退居其次。此外,多种非侵入性手术技术的发展,尤其是醋酸乌利司他作为一种病因性药物治疗的出现,已极大地改变了临床适应症。结果,在几乎20年没有相关更新之后,西班牙妇产科协会不得不两次更新子宫肌瘤管理方案。因此,我们认为有必要将我们的经验转化为针对子宫肌瘤患者的医疗护理方案,纳入这些新的治疗选择,并为他们选择最佳治疗方法。我们强调通过改善这类病症的临床诊断来实现患者目标和决策的重要性,这有助于加强个性化治疗,同时降低潜在风险和不必要的手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65d6/5592915/790661bfefe4/ijwh-9-607Fig1.jpg

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