Barnfield Lauren, Neale Edmund, Reynolds Sarah
a Department of Obstetrics and Gynaecology , South Wing, Bedford Hospital NHS Trust , Bedfordshire , UK.
J Obstet Gynaecol. 2018 Apr;38(3):301-304. doi: 10.1080/01443615.2017.1346594. Epub 2017 Sep 18.
The number of women undergoing induction of labour has risen steadily in recent years. Outpatient induction is becoming more common in the UK in response to the required increase in resources, although evidence supporting its safety is lacking. We reviewed the notes of low-risk women presenting for outpatient cervical ripening using prostaglandins over a five-year period, and compared our neonatal and maternal outcomes to local and national data. Of the 502 eligible women, 400 underwent outpatient treatment. Most women returned early, in labour. There were no foetal, neonatal or maternal deaths, and our neonatal morbidity compared favourably with local rates. Mode of delivery and major maternal complication rates were comparable to national maternity indicators. We conclude that outpatient cervical ripening following careful case selection does not appear to increase neonatal or maternal mortality or morbidity. It offers patients an alternative to traditional inpatient induction and may improve allocation of hospital resources. Impact statement We present a retrospective cohort study of neonatal and maternal outcomes in 502 women selected for outpatient cervical ripening for postmaturity at Bedford Hospital over the five-year period from 2010 to 2015. This study was conceived following a previous publication in this journal from Bedford Hospital in 2002 by Neale et al., which described the outcomes of 100 women who underwent outpatient cervical ripening. Our conclusions compare the results from the two studies. Out of our combined sample of 602 women, 491 were discharged home following administration of prostaglandins. This represents the largest sample size in the published literature on outpatient induction of labour, which was first undertaken in our unit in 1998 and is now widely practiced within the UK. Several publications, including the 2013 Cochrane review by Kelly et al. and a recent large survey of practice (Sharp et al. 2016 ) have highlighted the paucity of available data regarding the safety of this procedure as an outpatient. We therefore hope that the results of our study will be of interest to many maternity units who currently undertake or are considering to provide the facility for outpatient cervical ripening as a prelude to induction of labour.
近年来,接受引产的女性人数稳步上升。在英国,门诊引产因资源需求增加而变得越来越普遍,尽管缺乏支持其安全性的证据。我们回顾了五年期间使用前列腺素进行门诊宫颈成熟的低风险女性的病历,并将我们的新生儿和产妇结局与当地及全国数据进行了比较。在502名符合条件的女性中,400名接受了门诊治疗。大多数女性早早进入了产程。没有胎儿、新生儿或产妇死亡,我们的新生儿发病率与当地发病率相比情况良好。分娩方式和主要产妇并发症发生率与国家产妇指标相当。我们得出结论,在仔细筛选病例后进行门诊宫颈成熟似乎不会增加新生儿或产妇的死亡率或发病率。它为患者提供了一种替代传统住院引产的选择,并可能改善医院资源的分配。影响声明 我们对2010年至2015年期间在贝德福德医院因过期妊娠而被选进行门诊宫颈成熟的502名女性的新生儿和产妇结局进行了一项回顾性队列研究。这项研究是在2002年尼尔等人在本杂志上发表了一篇来自贝德福德医院的文章之后构思的,该文章描述了100名接受门诊宫颈成熟的女性的结局。我们的结论比较了两项研究的结果。在我们602名女性的合并样本中,491名在使用前列腺素后出院回家。这是已发表的关于门诊引产文献中最大的样本量,门诊引产于1998年在我们科室首次开展,现在在英国广泛应用。包括2013年凯利等人的Cochrane综述和最近一项大型实践调查(夏普等人,2016年)在内的几篇出版物都强调了关于该门诊手术安全性的可用数据匮乏。因此,我们希望我们的研究结果能引起许多目前正在进行或考虑提供门诊宫颈成熟设施作为引产前奏的产科单位的兴趣。