Basille D, De Dominicis F, Magois E, Andrejak C, Berna P, Jounieaux V
Service de pneumologie et réanimation respiratoire, CHU d'Amiens-Picardie, 80054 Amiens cedex 1, France.
Service de chirurgie thoracique, CHU d'Amiens-Picardie, 80054 Amiens cedex 1, France.
Rev Mal Respir. 2017 Nov;34(9):1022-1025. doi: 10.1016/j.rmr.2017.01.007. Epub 2017 Sep 18.
Endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive procedure used for the diagnosis of mediastinal and hilar lymphadenopathy.
We describe a case of mediastinitis appearing 15 days after an EBUS-TBNA procedure in a 79 years old male patient. The mediastinitis was treated surgically by thoracotomy with a wide excision of infected tissue requiring transplantation of a serratus anterior muscle flap pedicled on a branch of the thoracodorsal artery. It was coupled with broad spectrum antibiotics. This medico-surgical management led to a favorable outcome. Microbiological analysis of the mediastinal collections revealed two pathogens: Streptococcus constellatus (a germ present in the normal flora of the oral cavity) and Mycobacterium tuberculosis. A standard first line quadruple antituberculous drug regimen was subsequently given to the patient.
This episode of Streptococcus constellatus mediastinitis was a complication of the EBUS-TBNA procedure. The operating channel of the bronchoscope had probably been contaminated when aspirating the oral cavity secretions with subsequent needle contamination and a direct bacterial inoculation during the transbronchial mediastinal puncture. The severity of such a complication justifies a medical consultation in cases of fever or chest pain following an EBUS-TBNA procedure.
支气管内超声引导下经支气管针吸活检术(EBUS-TBNA)是一种用于诊断纵隔和肺门淋巴结病的微创操作。
我们描述了一例79岁男性患者在EBUS-TBNA术后15天出现纵隔炎的病例。通过开胸手术广泛切除感染组织并移植以胸背动脉分支为蒂的前锯肌瓣对纵隔炎进行了手术治疗。同时使用了广谱抗生素。这种药物和手术联合治疗取得了良好的效果。对纵隔积液的微生物分析发现了两种病原体:星座链球菌(口腔正常菌群中的一种细菌)和结核分枝杆菌。随后给患者使用了标准的一线四联抗结核药物方案。
此次星座链球菌纵隔炎是EBUS-TBNA手术的并发症。在经支气管纵隔穿刺过程中,用支气管镜吸取口腔分泌物时操作通道可能已被污染,随后针也被污染,导致细菌直接接种。这种并发症的严重性表明,在EBUS-TBNA术后出现发热或胸痛的情况下,有必要进行医学咨询。