环磷酰胺和/或蒽环类药物诱发乳腺癌患者溢泪：一种罕见的副作用。
Cyclophosphamide and/or Anthracyclines Induced Epiphora in Breast Cancer Patients: A Rare Side-effect.
作者信息
Kalra Ruchika, Chavada Bhavesh, Madhani Nishant R, Purohit Bhargav, Tripathi C B
机构信息
Department of Pharmacology, Government Medical College and Sir Takhtsinhji General Hospital, Bhavnagar-364001 (Gujarat), India.
Consultant Radiation Oncologist, Rajkot Cancer Hospital, N.P Cancer Institute, Rajkot-360001 (Gujarat), India.
出版信息
Curr Drug Saf. 2018;13(1):62-64. doi: 10.2174/1574886312666170919175614.
BACKGROUND
Two female breast cancer patients developed epiphora after administration of cyclophosphamide and/or anthracyclines based 2-day chemotherapy regimen. An ophthalmologist was consulted and no apparent cause was found.
CASE DESCRIPTION
Patients were managed by ciprofloxacin eye drops. Chemotherapy induced ocular complications are not uncommon, but under reported. Although epiphora is a mild reaction, if severe however, it can interfere with daily activities. Patients having chemotherapy induced ocular toxicity should go for ophthalmic examination to pick up ocular adverse effects of anticancer drugs and treat them at an early stage.
背景
两名女性乳腺癌患者在接受基于环磷酰胺和/或蒽环类药物的两日化疗方案后出现溢泪。咨询了眼科医生，但未发现明显病因。
病例描述
患者使用环丙沙星滴眼液进行治疗。化疗引起的眼部并发症并不罕见，但报道较少。尽管溢泪是一种轻微反应，但如果严重，会干扰日常活动。患有化疗引起的眼部毒性的患者应进行眼科检查，以发现抗癌药物的眼部不良反应并尽早治疗。
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