Shea Beverley J, Reeves Barnaby C, Wells George, Thuku Micere, Hamel Candyce, Moran Julian, Moher David, Tugwell Peter, Welch Vivian, Kristjansson Elizabeth, Henry David A
Ottawa Hospital Research Institute, Clinical Epidemiology Program, Ottawa, Canada
Bruyère Research Institute, Ottawa, Canada.
BMJ. 2017 Sep 21;358:j4008. doi: 10.1136/bmj.j4008.
The number of published systematic reviews of studies of healthcare interventions has increased rapidly and these are used extensively for clinical and policy decisions. Systematic reviews are subject to a range of biases and increasingly include non-randomised studies of interventions. It is important that users can distinguish high quality reviews. Many instruments have been designed to evaluate different aspects of reviews, but there are few comprehensive critical appraisal instruments. AMSTAR was developed to evaluate systematic reviews of randomised trials. In this paper, we report on the updating of AMSTAR and its adaptation to enable more detailed assessment of systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. With moves to base more decisions on real world observational evidence we believe that AMSTAR 2 will assist decision makers in the identification of high quality systematic reviews, including those based on non-randomised studies of healthcare interventions
已发表的医疗保健干预研究系统评价的数量迅速增加，这些评价被广泛用于临床和政策决策。系统评价容易受到一系列偏倚的影响，并且越来越多地纳入干预措施的非随机研究。使用者能够辨别高质量的评价非常重要。许多工具已被设计用于评估评价的不同方面，但全面的批判性评价工具却很少。AMSTAR是为评估随机试验的系统评价而开发的。在本文中，我们报告了AMSTAR的更新情况及其适应性调整，以便能够更详细地评估包括医疗保健干预措施的随机或非随机研究，或两者兼有的系统评价。随着越来越多的决策基于真实世界的观察性证据，我们相信AMSTAR 2将帮助决策者识别高质量的系统评价，包括那些基于医疗保健干预措施非随机研究的评价。
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