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颅骨瓣修复晚期鳞状细胞癌失败后颅骨缺损的姑息性覆盖:病例报告。

Palliative Coverage of Cranial Defect following Failed Cranial Flap for Advanced Squamous Cell Carcinoma: Case Report.

机构信息

1 Division of Neurological Surgery, Dartmouth-Hitchcock Medical Center , Lebanon , New Hampshire.

2 Division of Acute Care Surgery, University of Missouri School of Medicine , Columbia, Missouri.

出版信息

J Palliat Med. 2018 Jan;21(1):109-113. doi: 10.1089/jpm.2017.0258. Epub 2017 Sep 22.

Abstract

INTRODUCTION

With advanced-stage head and neck cancers, patients may develop large and/or complex wounds despite multiple reconstruction attempts. Wound coverage may require novel approaches to palliate the patient.

METHOD

We present the case of a 56-year-old female with advanced squamous cell carcinoma of the scalp and skull who required multiple surgical interventions. Despite our best reconstructive efforts, the patient subsequently developed scalp infection and sepsis, necessitating further debridement for source control. She then required coverage of the exposed dura and skull to prevent further infection.

RESULTS

The calvarial wound was covered with a dermal regeneration template and held in place by a vacuum-assisted closure (VAC) device. This coverage prevented additional infection and morbidity, was relatively easy and comfortable to manage, and demonstrated healing and development of granulation. Unfortunately, the patient succumbed to her systemic cancer before application of a palliative split-thickness skin graft.

CONCLUSION

A VAC device and dermal regeneration template constituted an excellent modality for managing the complex calvarial wound encountered by otolaryngology, neurosurgery, and burn/wound services. The technique provided appropriate palliation for a patient with advanced head and neck cancer.

摘要

简介

对于晚期头颈部癌症患者,尽管进行了多次重建尝试,仍可能会出现大而复杂的伤口。伤口覆盖可能需要采用新的方法来缓解患者的病情。

方法

我们介绍了一位 56 岁女性的病例,她患有头皮和颅骨的晚期鳞状细胞癌,需要多次手术干预。尽管我们进行了最佳的重建努力,但患者随后出现头皮感染和败血症,需要进一步清创以控制感染源。随后,她需要覆盖暴露的硬脑膜和颅骨,以防止进一步感染。

结果

使用真皮再生模板覆盖颅骨伤口,并通过负压辅助闭合(VAC)装置固定。这种覆盖物防止了进一步的感染和发病,管理相对简单舒适,并显示出愈合和肉芽形成。不幸的是,患者在应用姑息性中厚皮片移植前死于全身癌症。

结论

VAC 装置和真皮再生模板是耳鼻喉科、神经外科和烧伤/创伤科遇到的复杂颅骨伤口的极好治疗方法。该技术为晚期头颈部癌症患者提供了适当的缓解。

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