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下肢创伤重建中肌肉瓣与筋膜皮瓣的比较:多中心结果分析。

Muscle versus Fasciocutaneous Free Flaps in Lower Extremity Traumatic Reconstruction: A Multicenter Outcomes Analysis.

作者信息

Cho Eugenia H, Shammas Ronnie L, Carney Martin J, Weissler Jason M, Bauder Andrew R, Glener Adam D, Kovach Stephen J, Hollenbeck Scott T, Levin L Scott

机构信息

Durham, N.C.; and Philadelphia, Pa.

From the Division of Plastic and Reconstructive Surgery, Duke University Medical Center; the Department of Bioengineering, University of Pennsylvania; and the Division of Plastic Surgery and the Department of Orthopaedic Surgery, University of Pennsylvania Health System.

出版信息

Plast Reconstr Surg. 2018 Jan;141(1):191-199. doi: 10.1097/PRS.0000000000003927.

Abstract

BACKGROUND

Clinical indications are expanding for the use of fasciocutaneous free flaps in lower extremity traumatic reconstruction. The authors assessed the impact of muscle versus fasciocutaneous free flap coverage on reconstructive and functional outcomes.

METHODS

A multicenter retrospective review was conducted on all lower extremity traumatic free flaps performed at Duke University (1997 to 2013) and the University of Pennsylvania (2002 to 2013). Muscle and fasciocutaneous flaps were compared in two subgroups (acute trauma and chronic traumatic sequelae), according to limb salvage, ambulation time, and flap outcomes.

RESULTS

A total of 518 lower extremity free flaps were performed for acute traumatic injuries (n = 238) or chronic traumatic sequelae (n = 280). Muscle (n = 307) and fasciocutaneous (n = 211) flaps achieved similar cumulative limb salvage rates in acute trauma (90 percent versus 94 percent; p = 0.56) and chronic trauma subgroups (90 percent versus 88 percent; p = 0.51). Additionally, flap choice did not impact functional recovery (p = 0.83 for acute trauma; p = 0.49 for chronic trauma). Flap groups did not differ in the rates of flap thrombosis, flap salvage, flap loss, or tibial nonunion requiring bone grafting. Fasciocutaneous flaps were more commonly reelevated for subsequent orthopedic procedures (p < 0.01) and required fewer secondary skin-grafting procedures (p = 0.01). Reconstructive and functional outcomes remained heavily influenced by injury severity.

CONCLUSIONS

Muscle and fasciocutaneous free flaps achieved comparable rates of limb salvage and functional recovery. Flap selection should be guided by defect characteristics and reconstructive needs.

CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III.

摘要

背景

在下肢创伤重建中,筋膜皮瓣游离移植的临床应用指征正在不断扩大。作者评估了肌肉瓣与筋膜皮瓣游离移植覆盖对重建及功能结果的影响。

方法

对杜克大学(1997年至2013年)和宾夕法尼亚大学(2002年至2013年)所施行的所有下肢创伤游离皮瓣进行多中心回顾性研究。根据保肢情况、行走时间及皮瓣结果,在急性创伤和慢性创伤后遗症两个亚组中对肌肉瓣和筋膜皮瓣进行比较。

结果

共为急性创伤性损伤(n = 238)或慢性创伤后遗症(n = 280)施行518例下肢游离皮瓣移植。在急性创伤亚组(90%对94%;p = 0.56)和慢性创伤亚组(90%对88%;p = 0.51)中,肌肉瓣(n = 307)和筋膜皮瓣(n = 211)的累积保肢率相似。此外,皮瓣选择对功能恢复无影响(急性创伤p = 0.83;慢性创伤p = 0.49)。皮瓣组在皮瓣血栓形成率、皮瓣挽救率、皮瓣丢失率或需要植骨的胫骨骨不连发生率方面无差异。筋膜皮瓣更常用于后续骨科手术中的再次掀起(p < 0.01),且所需的二次植皮手术较少(p = 0.01)。重建和功能结果仍受损伤严重程度的严重影响。

结论

肌肉瓣和筋膜皮瓣游离移植的保肢率和功能恢复率相当。皮瓣选择应根据缺损特征和重建需求来指导。

临床问题/证据级别:治疗性,III级

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