Department of Neurology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, South Korea.
Department of Neurology, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, South Korea.
Headache. 2017 Nov;57(10):1583-1592. doi: 10.1111/head.13191. Epub 2017 Sep 22.
To investigate the frequency and impact of fibromyalgia among patients with chronic migraine (CM) and chronic tension-type headache (CTTH).
Fibromyalgia (FM) is a common comorbidity in patients with chronic headaches. CM and CTTH are the two common types of chronic headaches.
We conducted a cross-sectional study in neurology outpatient clinics of four university hospitals and selected first-visit 136 patients with CM and 35 patients with CTTH. FM was assessed based on the 2010 American College of Rheumatology diagnostic criteria.
The frequency of FM was significantly higher among patients with CM when compared to those with CTTH (91/136 [66.9%] vs 9/35 [25.7%], P < .001). Logistic regression analyses revealed an increased odds ratio (OR) for FM for patients with CM when compared to those with CTTH after adjustment for age, sex, anxiety, depression, and insomnia (OR = 3.6, 95% confidence interval = 1.1-11.4). Furthermore, CM patients with FM had higher scores in FM Impact Questionnaire compared to CTTH patients with FM (51.5 ± 16.3 vs 43.7 ± 18.7, P = .015). Comorbidity of FM was associated with increased frequency of photophobia, phonophobia, anxiety, depression, and insomnia among patients with CM. Such association was not noted among patients with CTTH.
FM based on 2010 American College of Rheumatology diagnostic criteria was more prevalent among patients with CM than those with CTTH. Some clinical features and comorbidities of CM varied with the presence of FM.
调查慢性偏头痛（CM）和慢性紧张型头痛（CTTH）患者中纤维肌痛（FM）的频率和影响。
纤维肌痛（FM）是慢性头痛患者常见的合并症。CM 和 CTTH 是两种常见的慢性头痛类型。
我们在四家大学医院的神经病学门诊进行了一项横断面研究，选择了首次就诊的 136 例 CM 患者和 35 例 CTTH 患者。根据 2010 年美国风湿病学会的诊断标准评估 FM。
与 CTTH 患者相比，CM 患者的 FM 频率明显更高（91/136 [66.9%] 与 9/35 [25.7%]，P < .001）。逻辑回归分析显示，在调整年龄、性别、焦虑、抑郁和失眠后，CM 患者发生 FM 的优势比（OR）高于 CTTH 患者（OR = 3.6，95%置信区间 = 1.1-11.4）。此外，与 CTTH 患者相比，CM 患者的 FM 患者 FM 影响问卷的评分更高（51.5 ± 16.3 与 43.7 ± 18.7，P = .015）。FM 的合并症与 CM 患者畏光、畏声、焦虑、抑郁和失眠的频率增加有关。而在 CTTH 患者中未观察到这种关联。
根据 2010 年美国风湿病学会的诊断标准，CM 患者的 FM 患病率高于 CTTH 患者。CM 患者的某些临床特征和合并症随 FM 的存在而变化。
