躲避内体：有效的胞质抗体递送
Dodging Endosomes: Effective Cytosolic Antibody Delivery.
作者信息
Löwik Dennis W P M
机构信息
Radboud University Nijmegen, Institute for Molecules and Materials, Bio-organic Chemistry, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands.
出版信息
Chembiochem. 2017 Nov 16;18(22):2196-2198. doi: 10.1002/cbic.201700510. Epub 2017 Oct 9.
PMID:28940648
Abstract
On the inside: New methodologies for delivering antibodies right into the cytosol of cells either directly across the plasma membrane or by allowing the antibody to escape from endosomes have been proposed recently by the Cardoso/Hackenberger and Futaki groups, respectively.
摘要
在内部
最近，Cardoso/Hackenberger团队和Futaki团队分别提出了将抗体直接穿过质膜或通过使抗体从内体中逸出而直接递送至细胞胞质溶胶的新方法。
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