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社区居住的老年男性 5 年内的剩余尿体积自然史:康科德健康和男性老龄化项目。

Natural history of post-void residual urine volume over 5 years in community-dwelling older men: The Concord Health and Ageing in Men Project.

机构信息

Centre for Education and Research on Ageing and Ageing and Alzheimer's Institute, Concord Hospital, University of Sydney, New South Wales, Australia.

Department of Urology, Concord Hospital, University of Sydney, New South Wales, Australia.

出版信息

Neurourol Urodyn. 2018 Mar;37(3):1068-1073. doi: 10.1002/nau.23415. Epub 2017 Sep 20.

Abstract

AIMS

To describe the natural history of post-void residual urine volume (PVR) in community-dwelling older men.

METHODS

The Concord Health and Ageing in Men Project involves a representative sample of community-dwelling men aged 70 and older in a defined geographic area of Sydney, Australia. PVR were measured at baseline and 2-year and 5-year follow-up. The measurements were considered valid when the voided volumes were 150 mL and over. Three-hundred twenty-nine men without conditions that are likely to alter PVR (neurological disorders, prostate cancer, and a history of urological treatment) were included in the analyses.

RESULTS

Baseline PVR were 0-49 mL in 183 men, 50-99 mL in 59 men, 100-199 mL in 72 men, 200-399 mL in 11 men, and 400 mL and over in 4 men. Thirteen out of 314 (4%) men with a baseline PVR of 0-199 mL and 2 out of 11 (18%) men with a baseline PVR of 200-399 mL had surgery for benign prostate enlargement (BPE) or indwelling catheterization over 5 years compared to three out of four men (75%) with a PVR of 400 mL and over. In all 101 men with a baseline PVR of less than 400 mL who did not receive urological treatment during follow-up and had valid PVR data for both 2-year and 5-year follow-up, PVR did not exceed 400 mL at either follow-up time point.

CONCLUSION

Conservative management may be appropriate for most older men with incidentally found elevated PVR of up to 400 mL.

摘要

目的

描述社区居住的老年男性的剩余尿体积(PVR)的自然史。

方法

Concord 健康与老龄化男性项目涉及澳大利亚悉尼一个特定地理区域的社区居住的 70 岁及以上的代表性男性样本。在基线和 2 年及 5 年随访时测量 PVR。当排空量为 150ml 及以上时,测量结果被认为是有效的。在分析中,有 329 名男性没有可能改变 PVR 的条件(神经障碍、前列腺癌和泌尿科治疗史)。

结果

183 名男性的基线 PVR 为 0-49ml,59 名男性为 50-99ml,72 名男性为 100-199ml,11 名男性为 200-399ml,4 名男性为 400ml 及以上。与基线 PVR 为 200-399ml 的 11 名男性中的 2 名(18%)和基线 PVR 为 0-199ml 的 314 名男性中的 13 名(4%)相比,在 5 年内有 4 名男性(100%)因良性前列腺增生(BPE)或留置导尿管而行手术,而 400ml 及以上的 PVR 中有 3 名男性(75%)接受了手术。在所有 101 名基线 PVR 小于 400ml 且在随访期间未接受泌尿科治疗且在 2 年和 5 年随访时均有有效 PVR 数据的男性中,在任何随访时间点,PVR 均未超过 400ml。

结论

对于大多数偶然发现高达 400ml 的升高的 PVR 的老年男性,保守治疗可能是合适的。

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