Esmaeili Anoosh, Bollmann Simone, Khalil Markus, De Rosa Roberta, Fichtlscherer Stephan, Akintuerk Hakan, Schranz Dietmar
Pediatric Heart Center of Hessen, Goethe University, Frankfurt/Main, Germany.
Pediatric Heart Center of Hessen, Justus Liebig University, Giessen, Germany.
J Interv Cardiol. 2018 Feb;31(1):106-111. doi: 10.1111/joic.12443. Epub 2017 Sep 20.
Percutaneous pulmonary valve implantation (PPVI) is nowadays an accepted treatment option to repair post-surgical conduit dysfunction of the right ventricular outflow tract (RVOT). In addition, many patients need a pulmonary valve to reconstruct a hemodynamically incompetent native or conduit free outflow tract. Based on our experience with percutaneous stent-valve placement in a cohort of 125 patients, we report here transvenous reconstruction of a conduit-free, patch repaired outflow tract by utilizing balloon-expandable stent-valves in 23 patients with a median age of 22 years (5-60 years). In 20 patients, the step-by-step procedure was performed uneventful with the aimed success. Severe RVOT dysfunction in term of a clinical relevant regurgitation could be changed to mild, as it was confirmed by follow-up color Doppler echocardiography. In a 5-year-old girl a Melody® valve was placed as a surgical-interventional hybrid approach. In one patient, the procedure was complicated by stent embolization during preparation of the RVOT for stent-valve implantation. Reposition of the embolized stent was nevertheless successful for finishing percutaneous valve-implantation. In one patient, surgical approach became necessary because of the inability to advance the balloon-mounted stent-valve through a pre-stented RVOT. Considering the current available balloon-expandable stent-valves, transvenous pulmonary valve implantation is feasible to treat even an incompetent conduit-free RVOT. However, preparation of the RVOT by pre-stenting, in most patients with more than two stents in telescope technique remains challenging. Reconstruction of RVOT by the current available valves is promising only for a carefully selected group of patients.
经皮肺动脉瓣植入术(PPVI)如今是修复右心室流出道(RVOT)术后管道功能障碍的一种可接受的治疗选择。此外,许多患者需要肺动脉瓣来重建血流动力学功能不全的天然或无管道流出道。基于我们在125例患者队列中进行经皮支架瓣膜置入的经验,我们在此报告23例中位年龄为22岁(5 - 60岁)的患者通过使用球囊扩张式支架瓣膜对无管道、补片修复的流出道进行经静脉重建。在20例患者中,逐步操作顺利完成并取得预期成功。随访彩色多普勒超声心动图证实,临床相关反流所致的严重RVOT功能障碍可转变为轻度。在一名5岁女孩中,采用了Melody®瓣膜作为外科 - 介入混合方法。在一名患者中,在为支架瓣膜植入准备RVOT的过程中发生了支架栓塞并发症。不过,栓塞支架的重新定位成功完成了经皮瓣膜植入。在一名患者中,由于无法将球囊装载的支架瓣膜推进到预先置入支架的RVOT中,因此需要采用外科手术方法。考虑到目前可用的球囊扩张式支架瓣膜,经静脉肺动脉瓣植入术即使对于无功能的无管道RVOT也是可行的治疗方法。然而,对于大多数采用套管技术置入两个以上支架的患者,通过预先置入支架来准备RVOT仍然具有挑战性。目前可用瓣膜对RVOT的重建仅对精心挑选的一组患者有前景。