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严重精神疾病女性的乳房 X 光检查:通过大型回顾性队列研究探讨差异。

Mammography Among Women With Severe Mental Illness: Exploring Disparities Through a Large Retrospective Cohort Study.

机构信息

Dr. Thomas and Dr. Mangurian are with the Department of Psychiatry, University of California, San Francisco (UCSF) Weill Institute for Neurosciences, where Dr. James was affiliated at the time of the study. Dr. James is currently a psychosomatic medicine fellow at Memorial Sloan-Kettering Cancer Center, New York. Dr. Mangurian is also with the UCSF Center for Vulnerable Populations at Zuckerberg San Francisco General Hospital, where Dr. Schillinger is affiliated. Dr. Schillinger is also with the Department of Medicine, UCSF School of Medicine. Dr. Vittinghoff and Ms. Creasman are with the Department of Epidemiology and Biostatistics, UCSF School of Medicine.

出版信息

Psychiatr Serv. 2018 Jan 1;69(1):48-54. doi: 10.1176/appi.ps.201600170. Epub 2017 Sep 15.

Abstract

OBJECTIVE

This study examined mammogram screening rates among women with severe mental illness by using a socioecological framework. Because it has been shown that people with severe mental illness receive less preventive health care overall, the analysis included psychosocial predictors of mammogram screening rates in a cohort of women with severe mental illness.

METHODS

This retrospective cohort study (N=14,651) used existing statewide data for women ages 48-67 in California with Medicaid insurance who received treatment in the specialty mental health care system. The primary outcome of interest was evidence of breast cancer screening via mammogram. The associations of each predictor of interest with mammogram screening were evaluated by using Poisson models with robust standard errors.

RESULTS

Across all demographic and diagnostic categories, rates of breast cancer screening in this cohort of women with severe mental illness fell below the national average. Only 26.3% (3,859/14,651) of women in the cohort received breast cancer screening in the past year. This study replicated previous findings that women with schizophrenia spectrum disorder and those with a comorbid substance use disorder are less likely to receive screening than those with other types of mental illness. In this cohort of women with severe mental illness, evidence of nonpsychiatric health care utilization was strongly associated with breast cancer screening (adjusted risk ratio=3.30, 95% confidence interval=2.61-4.16, p<.001).

CONCLUSIONS

The findings can inform efforts to improve breast cancer screening among women with severe mental illness, such as targeted outreach to population subsets and colocation of primary care services in mental health treatment settings.

摘要

目的

本研究采用社会生态学框架考察了严重精神疾病女性的乳房 X 光筛查率。由于已有研究表明,严重精神疾病患者总体上接受的预防保健较少,因此本分析纳入了严重精神疾病女性队列中乳房 X 光筛查率的心理社会预测因素。

方法

这是一项回顾性队列研究(N=14651),使用了加利福尼亚州患有 Medicaid 保险且在精神科专门医疗系统中接受治疗的 48-67 岁女性的现有全州数据。主要研究结果为乳房 X 光筛查的乳腺癌证据。使用具有稳健标准差的泊松模型评估了每个感兴趣预测因素与乳房 X 光筛查之间的关联。

结果

在所有人口统计学和诊断类别中,该严重精神疾病女性队列的乳腺癌筛查率低于全国平均水平。在该队列中,只有 26.3%(3859/14651)的女性在过去一年中接受了乳腺癌筛查。本研究复制了先前的发现,即精神分裂症谱系障碍患者和伴有共病物质使用障碍的患者比其他类型的精神疾病患者更不可能接受筛查。在该严重精神疾病女性队列中,非精神科医疗保健利用率的证据与乳腺癌筛查密切相关(调整后的风险比=3.30,95%置信区间=2.61-4.16,p<.001)。

结论

这些发现可以为改善严重精神疾病女性的乳腺癌筛查工作提供信息,例如针对特定人群的宣传和在精神卫生治疗环境中整合初级保健服务。

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