de Lorenzo Alberto, Liaño Fernando
Servicio de Nefrología, Hospital Universitario Ramón y Cajal, Red de Investigación Renal (REDinRED), Instituto Ramón y Cajal de Investigación Sanitaria (IRyCIS), Madrid, España.
Servicio de Nefrología, Hospital Universitario Ramón y Cajal, Red de Investigación Renal (REDinRED), Instituto Ramón y Cajal de Investigación Sanitaria (IRyCIS), Madrid, España.
Nefrologia. 2017 Sep-Oct;37(5):492-500. doi: 10.1016/j.nefro.2016.12.008.
It is well known that climate change greatly affects human health, even though there are few studies on renal outcomes. Heat waves have been found to increase cardiovascular and respiratory morbidity and mortality, as well as the risk of acute renal failure and hospitalisation due to renal diseases, with related mortality. Recurrent dehydration in people regularly exposed to high temperatures seems to be resulting in an unrecognised cause of proteinuric chronic kidney disease, the underlying pathophysiological mechanism of which is becoming better understood. However, beyond heat waves and extreme temperatures, there is a seasonal variation in glomerular filtration rate that may contribute to the onset of renal failure and electrolyte disorders during extremely hot periods. Although there are few references in the literature, serum sodium disorders seem to increase. The most vulnerable population to heat-related disease are the elderly, children, chronic patients, bedridden people, disabled people, people living alone or with little social contact, and socioeconomically disadvantaged people.
众所周知,气候变化对人类健康有很大影响,尽管关于肾脏结局的研究很少。热浪已被发现会增加心血管和呼吸系统疾病的发病率和死亡率,以及急性肾衰竭和因肾脏疾病住院的风险及相关死亡率。经常暴露于高温环境中的人反复脱水似乎是蛋白尿性慢性肾病一个未被认识的病因,其潜在的病理生理机制正逐渐被更好地理解。然而,除了热浪和极端温度外,肾小球滤过率存在季节性变化,这可能导致在极热时期肾衰竭和电解质紊乱的发生。尽管文献中提及较少,但血清钠紊乱似乎有所增加。最易患与热相关疾病的人群是老年人、儿童、慢性病患者、卧床不起的人、残疾人、独居或社交很少的人以及社会经济地位不利的人。