Department of Orthopaedic Surgery, Rothman Institute at Thomas Jefferson University, Philadelphia, Pennsylvania.
J Arthroplasty. 2018 Jan;33(1):277-283. doi: 10.1016/j.arth.2017.08.025. Epub 2017 Aug 30.
The quadriceps-sparing (QS) technique for total knee arthroplasty (TKA) was introduced to improve outcomes associated with the medial parapatellar (MP) approach. There is no clear consensus on what advantages, if any, QS provides.
We performed a meta-analysis of randomized controlled trials (RCTs) comparing the QS and MP techniques. PubMed, Ovid, and Scopus were assessed for relevant literature. Long-term (primary) outcomes and short-term (secondary) outcomes from 8 RCTs (579 TKAs) were analyzed using OpenMetaAnalyst (2016).
The QS approach did not demonstrate clinically significant advantages, but was associated with statistically and clinically significant increases in the primary outcomes of femoral (odds ratio [OR] 4.92, P = .005), tibial (OR 4.34, P = .01), and mechanical axis outliers (OR 4.77, P = .004). Secondary outcome assessments demonstrated increased surgical (mean differences [MD] 19.54, P < .001) and tourniquet time (MD 23.30, P < .001) for QS. Although statistically significant advantages for QS were identified in Knee Society Function scores at 1.5-3 months (MD 2.31, P = .004) and 2 years (MD 1.86, P < .001), these were not clinically significant (fell below the 6-point minimal clinically important difference).
The QS approach to TKA fails to demonstrate clinically significant advantages, but shows increased malalignment. This increased incidence of implant malalignment may predispose QS patients to early prosthesis failure. Because the QS approach may increases the risk of malalignment while providing no clear benefit compared to MP, we recommend against the routine use of the QS TKA approach.
为了改善内侧髌旁(MP)入路相关的结果,全膝关节置换术(TKA)引入了股四头肌保留(QS)技术。目前还没有明确的共识,即 QS 是否有任何优势。
我们对 QS 和 MP 技术的随机对照试验(RCT)进行了荟萃分析。评估了 PubMed、Ovid 和 Scopus 相关文献。使用 OpenMetaAnalyst(2016)分析了 8 项 RCT(579 例 TKA)的长期(主要)结果和短期(次要)结果。
QS 方法没有表现出临床显著优势,但与股骨(比值比 [OR] 4.92,P =.005)、胫骨(OR 4.34,P =.01)和机械轴离群值(OR 4.77,P =.004)的主要结果的统计学和临床显著增加相关。次要结果评估表明,QS 的手术(平均差异 [MD] 19.54,P <.001)和止血带时间(MD 23.30,P <.001)增加。尽管在 1.5-3 个月(MD 2.31,P =.004)和 2 年(MD 1.86,P <.001)时 QS 的膝关节协会功能评分有统计学意义的优势,但这些并没有临床意义(低于 6 分的最小临床重要差异)。
QS 方法在 TKA 中未能显示出临床显著优势,但显示出更高的对线不良。这种更高的植入物对线不良发生率可能使 QS 患者更容易早期假体失败。由于与 MP 相比,QS 方法可能增加对线不良的风险,同时没有明显的优势,我们建议反对常规使用 QS TKA 方法。