胫骨远端静脉旁路移植在严重肢体缺血中的应用及其在胫骨血管成形术失败后的作用。

Tibiodistal vein bypass in critical limb ischemia and its role after unsuccessful tibial angioplasty.

机构信息

Department of Vascular and Endovascular Surgery, Paracelsus Medical University Salzburg, Salzburg, Austria.

Department of Vascular and Endovascular Surgery, Paracelsus Medical University Salzburg, Salzburg, Austria.

出版信息

J Vasc Surg. 2018 Apr;67(4):1191-1198. doi: 10.1016/j.jvs.2017.07.127. Epub 2017 Sep 28.

Abstract

OBJECTIVE

Technical progress in angioplasty expanded its application to very distal arterial lesions of the lower extremity. In cases of unsuccessful angioplasty tibiodistal bypass surgery may be required for limb salvage. We investigated the long-term outcome of this technique in patients with critical limb ischemia. The purpose of this study was to evaluate whether tibiodistal bypasses done after unsuccessful tibial angioplasty had inferior patency, limb salvage, or survival rates compared with primary tibiodistal bypasses.

METHODS

This single-center, retrospective data analysis included all distal bypass procedures originating from a tibial artery. Primary study end points were primary patency, secondary patency, and limb salvage. Secondary end points included survival, wound healing, and systemic and local complications. Society for Vascular Surgery reporting standards were applied.

RESULTS

There were 61 tibiodistal vein bypasses for critical limb ischemia performed in 23 years. Indications for tibiodistal bypass was Rutherford category 5 in 41 cases (67%) and category 6 in 20 cases (33%). Procedures were allocated to group A (primary bypass; n = 28) and group B (bypass after unsuccessful tibial angioplasty; n = 33). Primary patency was 55% versus 53% at 1 year and 47% versus 44% at 3 years (P = .58). Secondary patency was 59% versus 64% at 1 year and 52% versus 55% at 3 years (P = .36). Limb salvage was 96% versus 90% at 1 year and 91% versus 85% at 3 years (P = .44). Overall survival rates were 91% versus 97% at 1 year and 85% versus 92% at 3 years (P = .76). The median follow-up was 4.0 years in group A and 4.9 years in group B. In multivariate analyses for loss of primary patency and limb loss, no significant predictors could be identified.

CONCLUSIONS

This study showed that tibiodistal vein bypass is a feasible, efficient, and safe technique in patients with critical limb ischemia. It provides acceptable primary and secondary patency rates to prevent major amputation and ensure survival. Previous unsuccessful tibial angioplasty had no significant impact on tibiodistal vein bypass outcome. This technique should be part of the armamentarium of vascular surgeons.

摘要

目的

血管成形术技术的进步使其应用范围扩大到下肢非常远端的动脉病变。在血管成形术不成功的情况下,可能需要进行胫腓骨远端旁路手术以保留肢体。我们研究了该技术在有严重肢体缺血的患者中的长期结果。本研究的目的是评估与初次胫腓骨远端旁路相比,经不成功的胫骨血管成形术后行胫腓骨远端旁路的通畅率、保肢率或生存率是否较低。

方法

这项单中心回顾性数据分析包括所有源自胫动脉的远端旁路手术。主要研究终点是一期通畅率、二期通畅率和保肢率。次要终点包括生存率、伤口愈合情况以及全身和局部并发症。应用血管外科学会报告标准。

结果

23 年间共行 61 例因严重肢体缺血而进行的胫腓骨远端静脉旁路手术。胫腓骨远端旁路的适应证为 Rutherford 分类 5 级 41 例(67%)和 6 级 20 例(33%)。手术分为 A 组(初次旁路;n=28)和 B 组(经不成功的胫骨血管成形术后的旁路;n=33)。1 年时一期通畅率分别为 55%和 53%,3 年时分别为 47%和 44%(P=0.58)。二期通畅率分别为 59%和 64%,1 年时分别为 52%和 55%(P=0.36)。1 年时保肢率分别为 96%和 90%,3 年时分别为 91%和 85%(P=0.44)。1 年时总体生存率分别为 91%和 97%,3 年时分别为 85%和 92%(P=0.76)。A 组的中位随访时间为 4.0 年,B 组为 4.9 年。多变量分析显示,一期通畅率和保肢率丧失均无显著预测因素。

结论

本研究表明,对于严重肢体缺血患者,胫腓骨远端静脉旁路是一种可行、有效且安全的技术。它可提供可接受的一期和二期通畅率,以预防主要截肢并确保生存率。先前不成功的胫骨血管成形术对胫腓骨远端静脉旁路的结果无显著影响。该技术应成为血管外科医生的治疗手段之一。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索