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Mesothelin-Specific Immune Responses and Targeted Immunotherapy for Mesothelin-Expressing Tumors.间皮素特异性免疫反应及针对表达间皮素肿瘤的靶向免疫治疗
EBioMedicine. 2017 Oct;24:16-17. doi: 10.1016/j.ebiom.2017.09.033. Epub 2017 Sep 25.
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Generation of a Transgenic BALB/c Mouse Line With Selective Expression of Human Mesothelin in Thyroid Gland: Application in Mesothelin-targeted Immunotherapy.生成一种在甲状腺中选择性表达人间皮素的转基因 BALB/c 小鼠系：在间皮素靶向免疫治疗中的应用。
J Immunother. 2019 May;42(4):119-125. doi: 10.1097/CJI.0000000000000263.
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The role of mesothelin in tumor progression and targeted therapy.间皮素在肿瘤进展和靶向治疗中的作用。
Anticancer Agents Med Chem. 2013 Feb;13(2):276-80. doi: 10.2174/1871520611313020014.
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Engineering Tumor Hypersusceptibility to Checkpoint Immunotherapy.工程化肿瘤对免疫检查点疗法的超敏感性
Trends Cancer. 2017 Oct;3(10):675-677. doi: 10.1016/j.trecan.2017.08.002. Epub 2017 Sep 4.
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Calling time on the immunotherapy gold rush.为免疫疗法热潮敲响丧钟。
Lancet Oncol. 2017 Aug;18(8):981. doi: 10.1016/S1470-2045(17)30521-1. Epub 2017 Jul 26.
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Mesothelin-targeted agents in clinical trials and in preclinical development.正在临床试验和临床前开发中进行的间皮素靶向药物。
Mol Cancer Ther. 2012 Mar;11(3):517-25. doi: 10.1158/1535-7163.MCT-11-0454. Epub 2012 Feb 17.
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A human single-domain antibody elicits potent antitumor activity by targeting an epitope in mesothelin close to the cancer cell surface.一种人类单域抗体通过靶向接近癌细胞表面的间皮素表位，引发强烈的抗肿瘤活性。
Mol Cancer Ther. 2013 Apr;12(4):416-26. doi: 10.1158/1535-7163.MCT-12-0731. Epub 2013 Jan 31.
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What advances have been made in immune-therapy for renal cell carcinoma?肾细胞癌免疫治疗取得了哪些进展？
Future Oncol. 2017 Apr;13(8):665-668. doi: 10.2217/fon-2017-0026. Epub 2017 Feb 10.
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Efficient growth suppression in pancreatic cancer PDX model by fully human anti-mesothelin CAR-T cells.全人源抗间皮素CAR-T细胞在胰腺癌PDX模型中有效抑制肿瘤生长
Protein Cell. 2017 Dec;8(12):926-931. doi: 10.1007/s13238-017-0472-9.
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Cancer immunotherapy: broadening the scope of targetable tumours.癌症免疫疗法：拓宽可靶向肿瘤的范围。
Open Biol. 2018 Jun;8(6). doi: 10.1098/rsob.180037.
引用本文的文献
1
Mesothelin expression and its prognostic role according to microsatellite instability status in colorectal adenocarcinoma.间皮素在结直肠癌中的表达及其根据微卫星不稳定性状态的预后作用。
Medicine (Baltimore). 2019 Jun;98(26):e16207. doi: 10.1097/MD.0000000000016207.
本文引用的文献
1
Mesothelin-specific Immune Responses Predict Survival of Patients With Brain Metastasis.针对间皮素的免疫反应可预测脑转移患者的生存情况。
EBioMedicine. 2017 Sep;23:20-24. doi: 10.1016/j.ebiom.2017.08.024. Epub 2017 Aug 30.
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Mesothelin Immunotherapy for Cancer: Ready for Prime Time?间皮素免疫疗法治疗癌症：准备好进入黄金时代了吗？
J Clin Oncol. 2016 Dec;34(34):4171-4179. doi: 10.1200/JCO.2016.68.3672. Epub 2016 Oct 31.
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Clinical impacts of mesothelin expression in gastrointestinal carcinomas.间皮素在胃肠道癌中的表达的临床影响
World J Gastrointest Pathophysiol. 2016 May 15;7(2):218-22. doi: 10.4291/wjgp.v7.i2.218.
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ERC/mesothelin is expressed in human gastric cancer tissues and cell lines.ERC/间皮素在人胃癌组织和细胞系中表达。
Oncol Rep. 2014 Jan;31(1):27-33. doi: 10.3892/or.2013.2803. Epub 2013 Oct 22.
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C-ERC/mesothelin provokes lymphatic invasion of colorectal adenocarcinoma.C-ERC/间皮素促进结直肠腺癌的淋巴管侵犯。
J Gastroenterol. 2014 Jan;49(1):81-92. doi: 10.1007/s00535-013-0773-6. Epub 2013 Mar 20.
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Intracellular localization of mesothelin predicts patient prognosis of extrahepatic bile duct cancer.间皮素的细胞内定位可预测肝外胆管癌患者的预后。
Int J Oncol. 2012 Dec;41(6):2109-18. doi: 10.3892/ijo.2012.1662. Epub 2012 Oct 15.
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Luminal membrane expression of mesothelin is a prominent poor prognostic factor for gastric cancer.间皮素在腔膜表面的表达是胃癌预后不良的一个显著因素。
Br J Cancer. 2012 Jun 26;107(1):137-42. doi: 10.1038/bjc.2012.235. Epub 2012 May 29.
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Co-expression of mesothelin and CA125 correlates with unfavorable patient outcome in pancreatic ductal adenocarcinoma.间皮素和 CA125 的共表达与胰腺导管腺癌患者不良预后相关。
Pancreas. 2011 Nov;40(8):1276-82. doi: 10.1097/MPA.0b013e318221bed8.
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Soluble member(s) of the mesothelin/megakaryocyte potentiating factor family are detectable in sera from patients with ovarian carcinoma.在卵巢癌患者的血清中可检测到间皮素/巨核细胞增强因子家族的可溶性成员。
Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11531-6. doi: 10.1073/pnas.96.20.11531.
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