Phelan Michael P, Reineks Edmunds Z, Berriochoa Jacob P, Schold Jesse D, Hustey Fredric M, Chamberlin Janelle, Kovach Annmarie
Center for Emergency Medicine.
Laboratory Medicine.
Am J Clin Pathol. 2017 Oct 1;148(4):330-335. doi: 10.1093/ajcp/aqx082.
Hemolyzed blood samples commonly occur in hospital emergency departments (EDs). Our objective was to determine whether replacing standard large-volume/high-vacuum sample tubes with low-volume/low-vacuum tubes would significantly affect ED hemolysis.
This was a prospective intervention of the use of small-volume/vacuum collection tubes. We evaluated all potassium samples in ED patients and associated hemolysis. We used χ2 tests to compare hemolysis incidence prior to and following utilization of small tubes for chemistry collection.
There were 35,481 blood samples collected during the study period. Following implementation of small-volume tubes, overall hemolysis decreased from a baseline of 11.8% to 2.9% (P < .001) with corresponding reductions in hemolysis with comment (8.95% vs 1.99%; P < .001) gross hemolysis (2.84% vs 0.90%; P < .007).
This work demonstrates that significant improvements in ED hemolysis can be achieved by utilization of small-volume/vacuum sample collection tubes.
溶血血样在医院急诊科很常见。我们的目的是确定用小容量/低真空采血管取代标准的大容量/高真空采血管是否会显著影响急诊科的溶血情况。
这是一项关于使用小容量/真空采血管的前瞻性干预研究。我们评估了急诊科患者所有的血钾样本及相关溶血情况。我们使用卡方检验比较了使用小采血管进行化学检测前后的溶血发生率。
研究期间共采集了35481份血样。采用小容量采血管后，总体溶血率从基线的11.8%降至2.9%（P <.001），伴有注释的溶血（8.95%对1.99%；P <.001）和严重溶血（2.84%对0.90%；P <.007）也相应降低。
这项研究表明，使用小容量/真空采血管可显著改善急诊科的溶血情况。
