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韩国脑瘫数据库:关于韩国脑瘫特征的报告。

Korean Database of Cerebral Palsy: A Report on Characteristics of Cerebral Palsy in South Korea.

作者信息

Yim Shin-Young, Yang Chung-Yong, Park Joo Hyun, Kim Min Young, Shin Yong-Beom, Kang Eun-Young, Lee Zee-Ihn, Kwon Bum-Sun, Chang Ji Chan, Kim Seong Woo, Kim Myeong-Ok, Kwon Jeong-Yi, Jung Han-Young, Sung In Young

机构信息

Department of Physical Medicine and Rehabilitation, Ajou University School of Medicine, Suwon Korea.

Rehabilitation Institute of Chicago, Chicago, IL, USA and The Seum Hospital, Jeonju, Korea.

出版信息

Ann Rehabil Med. 2017 Aug;41(4):638-649. doi: 10.5535/arm.2017.41.4.638. Epub 2017 Aug 31.

Abstract

OBJECTIVE

To introduce the Korean Database of Cerebral Palsy (KDCP) and to provide the first report on characteristics of subjects with cerebral palsy (CP).

METHODS

The KDCP is a nationwide database of subjects with CP, which includes a total of 773 subjects. Characteristics such as demography, birth history, onset and type of CP, brain magnetic resonance imaging (MRI) findings, functional ability and accompanying impairments, were extracted and analyzed.

RESULTS

Preterm delivery and low birth weight were found in 59.51% and 60.28% of subjects, respectively. Postnatally acquired CP was 15.3%. The distribution of CP was 87.32%, 5.17%, and 1.81% for spastic, dyskinetic, and ataxic types, respectively. Functional ability was the worst in dyskinetic CP, as compared to other types of CP. Speech-language disorder (43.9%), ophthalmologic impairment (32.9%), and intellectual disability (30.3%) were the three most common accompanying impairments. The number of accompanying impairments was elevated in subjects with preterm birth and low birth weight. Brain MRI showed normal findings, malformations, and non-malformations in 10.62%, 9.56%, and 77.35% of subjects, respectively. Subjects with normal MRI findings had better functional ability than subjects with other MRI findings. MRI findings of a non-malformation origin, such as periventricular leukomalacia, were more common in subjects with preterm birth and low birth weight.

CONCLUSION

The KDCP and its first report are introduced in this report, wherein the KDCP established agreement on terminologies of CP. This study added information on the characteristics of subjects with CP in South Korea, which can now be compared to those of other countries and ethnicities.

摘要

目的

介绍韩国脑瘫数据库(KDCP),并提供关于脑瘫(CP)患者特征的首份报告。

方法

KDCP是一个全国性的脑瘫患者数据库,共纳入773名患者。提取并分析了人口统计学、出生史、脑瘫的发病及类型、脑磁共振成像(MRI)结果、功能能力及伴随损伤等特征。

结果

分别有59.51%和60.28%的患者存在早产和低出生体重情况。产后获得性脑瘫占15.3%。痉挛型、运动障碍型和共济失调型脑瘫的分布分别为87.32%、5.17%和1.81%。与其他类型的脑瘫相比,运动障碍型脑瘫患者的功能能力最差。言语障碍(43.9%)、眼科损伤(32.9%)和智力残疾(30.3%)是三种最常见的伴随损伤。早产和低出生体重患者的伴随损伤数量更多。脑MRI显示,分别有10.62%、9.56%和77.35%的患者结果正常、存在畸形和非畸形情况。MRI结果正常的患者比其他MRI结果的患者功能能力更好。非畸形起源的MRI结果,如脑室周围白质软化,在早产和低出生体重患者中更常见。

结论

本报告介绍了KDCP及其首份报告,其中KDCP对脑瘫术语达成了一致。本研究补充了韩国脑瘫患者特征的信息,现在可以与其他国家和种族的特征进行比较。

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