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腔静脉三尖瓣峡部消融术后等待自发早期再连接的时间的研究:一项单中心随机试验。

Interest of waiting time for spontaneous early reconnection after cavotricuspid isthmus ablation: A monocentric randomized trial.

作者信息

Marchandise Sébastien, Scavée Christophe, Barbraud Cynthia, de Meester de Ravenstein Christophe, Balola Bagalwa Mittérand, Goesaert Cédric, Reis-Pinheiro Ivone, le Polain de Waroux Jean-Benoit

机构信息

Division of Cardiology, Department of Cardiovascular Diseases, Cliniques Universitaires St-Luc, Université Catholique de Louvain, Brussels, Belgium.

出版信息

Pacing Clin Electrophysiol. 2017 Dec;40(12):1440-1445. doi: 10.1111/pace.13207. Epub 2017 Nov 22.

Abstract

INTRODUCTION

The aim of this study was to determine the rate of recurrent atrial flutter (AFl) after isolated cavotricuspid isthmus (CTI) ablation and to evaluate the impact of a waiting period with the search for early resumption of the CTI block on the long-term outcome.

METHOD

Three hundred and nineteen consecutive patients referred for typical AFl ablation were randomly assigned to CTI ablation with continuous reevaluation of the CTI block during 30 minutes and early reablation if needed (waiting time [WT] + group, n  =  155) or to CTI ablation with no waiting period after proven bidirectional CTI block (WT - group, n  =  164). All patients were regularly followed-up.

RESULT

In the WT+ group, 10 patients (6%) presented a recovery across the CTI (time to recovery: 17 ± 7') and were reablated at the end of the waiting period. After a median follow-up of 21 months, the rate of recurrent AFl was significantly higher in the WT - group as compared to the WT+ group (11.6% [19/164] vs 2.5% [4/155], respectively; P  =  0.007). However, no significant differences in the subsequent rate of AF were observed between the two groups (29% [WT -] vs 32% [WT+], P  =  0.66). During the follow-up, 28 patients from the WT - group underwent a second ablation procedure (16 AFl redo and 12 AF ablation) versus 10 patients form the WT+ group (three AFl redo and seven AF ablation).

CONCLUSION

Waiting 30 minutes after CTI ablation to check for early resumption and early reablation allows for decreasing significantly the rate of recurrent atrial flutter.

摘要

引言

本研究的目的是确定孤立性三尖瓣峡部(CTI)消融术后房扑(AFl)复发率,并评估等待期以及寻找CTI阻滞早期恢复情况对长期预后的影响。

方法

319例因典型AFl消融而转诊的连续患者被随机分为两组,一组在CTI消融过程中持续30分钟重新评估CTI阻滞情况,必要时进行早期再次消融(等待时间[WT]+组,n = 155);另一组在证实双向CTI阻滞后不设等待期直接进行CTI消融(WT-组,n = 164)。所有患者均接受定期随访。

结果

在WT+组中,10例患者(6%)出现CTI恢复(恢复时间:17±7分钟),并在等待期结束时再次接受消融。中位随访21个月后,WT-组的房扑复发率显著高于WT+组(分别为11.6%[19/164]和2.5%[4/155];P = 0.007)。然而,两组后续房颤发生率无显著差异(WT-组为29%,WT+组为32%,P = 0.66)。随访期间,WT-组有28例患者接受了第二次消融手术(16例房扑再次消融和12例房颤消融),而WT+组有10例患者(3例房扑再次消融和7例房颤消融)。

结论

CTI消融后等待30分钟检查早期恢复情况并进行早期再次消融可显著降低房扑复发率。

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