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妊娠糖尿病:1 型糖尿病患者的医疗结局更差,但妊娠糖尿病患者的心理结局更差。

Diabetes in pregnancy: worse medical outcomes in type 1 diabetes but worse psychological outcomes in gestational diabetes.

机构信息

School of Medicine, Galway Diabetes Research Centre.

School of Psychology, National University of Ireland Galway, University Road, Galway, Ireland H91 TK33.

出版信息

QJM. 2017 Nov 1;110(11):721-727. doi: 10.1093/qjmed/hcx106.

Abstract

BACKGROUND

Women with diabetes experience an increased risk of adverse pregnancy outcomes.

AIM

We aim to describe and quantify the psychological impact of the diagnosis of diabetes in pregnant women with type 1 diabetes and gestational diabetes mellitus (GDM) compared to each other and to their counterparts without diabetes.

DESIGN

This is a survey-based study with prospective collection of pregnancy outcome data.

METHODS

A total of 218 pregnant women (50% with diabetes) were administered questionnaires relating to psychological health. Maternal and neonatal characteristics and pregnancy outcomes were collected. Associations between key psychometric and health outcome variables were examined.

RESULTS

At least 25% of women in all three pregnancy groups had scores indicating affective distress in at least one domain. Compared to those with type 1 diabetes, women with GDM evidenced a greater number of uplifts in pregnancy (U = 94, P = 0.041), but also higher levels of overall anxiety (U = 92, P = 0.03) and stress (U = 82, P < 0.01). Women with GDM also had significantly elevated overall depression scores, compared with the control group (U = 34, P = 0.02). Both groups of women with diabetes had clinically elevated levels of diabetes-related distress. There were no associations between maternal psychological variables and pregnancy outcomes.

CONCLUSIONS

This work highlights a potential role for targeted psychological interventions to address and relieve symptoms of anxiety and depression among pregnant women with diabetes.

摘要

背景

患有糖尿病的女性会面临增加的不良妊娠结局风险。

目的

我们旨在描述和量化 1 型糖尿病和妊娠糖尿病(GDM)孕妇与无糖尿病孕妇相比,糖尿病诊断对其心理健康的影响。

设计

这是一项基于问卷调查的前瞻性研究,收集妊娠结局数据。

方法

共纳入 218 名孕妇(50%患有糖尿病),对其进行与心理健康相关的问卷调查。收集产妇和新生儿特征及妊娠结局。检查关键心理计量和健康结果变量之间的相关性。

结果

在所有三组妊娠孕妇中,至少有 25%的孕妇在至少一个领域的评分显示出情感困扰。与 1 型糖尿病孕妇相比,GDM 孕妇在妊娠期间的情绪提升(U = 94,P = 0.041)更多,但整体焦虑(U = 92,P = 0.03)和压力(U = 82,P < 0.01)水平也更高。与对照组相比,GDM 孕妇的总体抑郁评分也显著升高(U = 34,P = 0.02)。两组糖尿病孕妇的糖尿病相关困扰均处于临床显著水平。母亲的心理变量与妊娠结局之间无相关性。

结论

这项研究强调了针对患有糖尿病的孕妇进行有针对性的心理干预,以缓解和减轻焦虑和抑郁症状的潜在作用。

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