From the *Department of Molecular Imaging and Nuclear Medicine, Indraprastha Apollo Hospitals, Sarita Vihar, Delhi; and †Department of Laboratory Medicine, Sir H. N. Reliance Foundation Hospital, Prarthana Samaj, Girgaon, Mumbai, India.
Clin Nucl Med. 2017 Dec;42(12):e509-e510. doi: 10.1097/RLU.0000000000001874.
Ga-prostate-specific membrane antigen (PSMA) has gained increasing interest as a target molecule in imaging of prostate cancer because of its selective overexpression in local prostate cancer lesions and metastasis. We report a case of a 62-year-old man with raised serum prostate-specific antigen levels who presented for Ga-PSMA HBED-CC simultaneous PET/MRI for prostate cancer evaluation. A PSMA-nonavid PI-RADS 5 (Prostate Imaging-Reporting and Data System) lesion was confirmed as adenocarcinoma on histopathology. The PSMA-avid lesions were noted in the calvarium and lung, with the calvarial lesion confirmed to be of tubercular etiology on biopsy, and both lesions subsequently responded to antitubercular treatment.
前列腺特异性膜抗原（PSMA）在前列腺癌的成像中作为靶分子越来越受到关注，因为它在局部前列腺癌病变和转移中选择性过表达。我们报告了一例 62 岁男性，其血清前列腺特异性抗原水平升高，因前列腺癌评估而行 Ga-PSMA HBED-CC 同时 PET/MRI 检查。PSMA-非阿维 PI-RADS 5（前列腺成像报告和数据系统）病变在组织病理学上确认为腺癌。PSMA 阳性病变见于颅骨和肺部，颅骨病变经活检证实为结核病因，随后两种病变均对抗结核治疗有反应。
