a Department of Ophthalmology , New York University , New York , New York , USA.
b Vitreous Retina Macula Consultants of New York , New York , New York , USA.
Ocul Immunol Inflamm. 2019;27(2):251-256. doi: 10.1080/09273948.2017.1381271. Epub 2017 Oct 17.
To illustrate the rate of endogenous endophthalmitis associated with fungemia and evaluate the importance of screening in a public city hospital.
A retrospective review was performed on all inpatient ophthalmology consults for fungemia from 2010 to 2015. Clinical histories, ocular examinations, and microbial cultures were reviewed.
Of 95 patients (mean age 51.6 years, 75% male) with fungemia, 9/95 (9.5%) demonstrated intraocular involvement. Of these nine patients, two were unable to participate in the ophthalmic exam due to intubation, while the remaining seven reported no changes in their vision. Two patients had their antifungal medications adjusted to optimize intraocular penetration and one patient progressed to develop vitreous involvement but died before further escalation of care occurred.
All involved individuals in this study were either non-communicative or without visual complaints. This suggests that routine screening should still be recommended, especially in a public hospital setting.
阐明与真菌血症相关的内源性眼内炎的发生率，并评估在一家公立城市医院进行筛查的重要性。
对 2010 年至 2015 年所有真菌血症住院眼科会诊进行回顾性分析。回顾了临床病史、眼部检查和微生物培养结果。
在 95 例（平均年龄 51.6 岁，75%为男性）真菌血症患者中，9/95（9.5%）存在眼内受累。这 9 例患者中，有 2 例因插管而无法进行眼科检查，而其余 7 例报告视力无变化。2 名患者调整了抗真菌药物以优化眼内穿透性，1 名患者进展为玻璃体内受累，但在进一步升级治疗前死亡。
在这项研究中，所有涉及的个体要么无法交流，要么没有视力投诉。这表明，即使在公立医院环境下，仍应推荐常规筛查。
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