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Concurrent therapy of chronic lymphocytic leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia utilizing CD19-targeted CAR T-cells.

作者信息

Geyer Mark B, Manjunath Shwetha H, Evans Andrew G, Park Jae H, Davila Marco L, Cutler Corey S, Wang Xiuyan, Wang Yongzeng, Senechal Brigitte, Rivière Isabelle, Sadelain Michel, Liesveld Jane L, Brentjens Renier J

机构信息

a Department of Medicine , Memorial Sloan Kettering Cancer Center , New York City , NY , USA.

b Center for Cell Engineering , Memorial Sloan Kettering Cancer Center , New York City , NY , USA.

出版信息

Leuk Lymphoma. 2018 Jul;59(7):1717-1721. doi: 10.1080/10428194.2017.1390237. Epub 2017 Oct 18.

Abstract
摘要

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本文引用的文献

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CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients.
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T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production.
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