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应用 PIXE/PIGE 技术对根龋模型中 Ca 和 F 进行顺序测量。

Use of PIXE/PIGE for sequential Ca and F measurements in root carious model.

机构信息

Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry, Osaka, Japan.

Division of Clinical Cariology and Endodontology, Health Sciences University of Hokkaido Graduate School of Dentistry, Hokkaido, Japan.

出版信息

Sci Rep. 2017 Oct 18;7(1):13450. doi: 10.1038/s41598-017-14041-4.

DOI:10.1038/s41598-017-14041-4
PMID:29044178
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5647451/
Abstract

The progress of caries has conventionally been evaluated by checking changes in mineral density using transverse microradiography (TMR). Recent advances have seen development of a new measurement system, using in-air micro proton induced X-ray/gamma-ray emission (PIXE/PIGE). PIXE/PIGE enables analysis of distributions and concentrations of multiple mineral elements in a carious lesion. The aim of this study was to evaluate the effectiveness of PIXE/PIGE for investigating the development of root caries. In summary, we successfully established a multi-elemental sequential measuring method using in-air micro-PIXE/PIGE to identify the dynamic distributions and concentrations of Ca and F in human root dentin. The PIXE/PIGE potentially offers a useful advantageous technique for studying carious development by using as a combination with conventional techniques such as TMR and Micro-computed tomography (µCT).

摘要

龋病的进展传统上是通过横切显微放射照相术 (TMR) 检查矿物质密度的变化来评估的。最近的进展见证了一种新的测量系统的发展，该系统使用空气微质子诱导 X 射线/伽马射线发射 (PIXE/PIGE)。PIXE/PIGE 能够分析龋齿病变中多种矿物质元素的分布和浓度。本研究旨在评估 PIXE/PIGE 用于研究根龋发展的有效性。总之，我们成功地建立了一种使用空气微 PIXE/PIGE 的多元素顺序测量方法，以识别人类牙根牙本质中 Ca 和 F 的动态分布和浓度。PIXE/PIGE 可能为研究龋齿发展提供一种有用的有利技术，可与 TMR 和微计算机断层扫描 (µCT) 等常规技术结合使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7834/5647451/e5c00598af8b/41598_2017_14041_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7834/5647451/19cf3fc1c662/41598_2017_14041_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7834/5647451/0a664ae40f7a/41598_2017_14041_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7834/5647451/5c12fef6173f/41598_2017_14041_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7834/5647451/626b82640ed1/41598_2017_14041_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7834/5647451/e5c00598af8b/41598_2017_14041_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7834/5647451/19cf3fc1c662/41598_2017_14041_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7834/5647451/0a664ae40f7a/41598_2017_14041_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7834/5647451/5c12fef6173f/41598_2017_14041_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7834/5647451/626b82640ed1/41598_2017_14041_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7834/5647451/e5c00598af8b/41598_2017_14041_Fig5_HTML.jpg

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