Department of Cardiology, Northwick Park Hospital, Harrow, UK.
Department of Cardiology, Royal Brompton Hospital, Sydney Street, London, SW3 6NP, UK.
Curr Cardiol Rep. 2017 Oct 18;19(12):121. doi: 10.1007/s11886-017-0935-x.
Stress echocardiography (SE) is a well-established technique for the diagnosis and risk stratification of patients with known or suspected coronary artery disease (CAD). This review article summarizes the status of SE in CAD, including testing protocols, clinical efficacy and current use of newer technologies: myocardial perfusion, strain imaging, three-dimensional echocardiography and adjunctive carotid ultrasonography.
Recent major findings in SE include the clinical value of myocardial perfusion imaging in multicentre studies, as well as when added to left ventricular (LV) wall motion assessment in clinical service. Additionally, SE has been shown to be more cost-effective than exercise ECG in patients with low-intermediate pre-test probability of CAD. Adjunctive atherosclerosis imaging by carotid ultrasonography (CU) to ischaemia testing by SE provides synergistic prognostic value, equivalent to hybrid imaging by PET-CT. Despite the development of newer and more expensive imaging modalities, SE remains the cornerstone for the assessment of CAD and has excellent clinical efficacy, is safe and is cost-effective.
超声心动图负荷试验(SE)是一种成熟的技术,用于诊断和危险分层已知或疑似冠状动脉疾病(CAD)的患者。本文综述了 SE 在 CAD 中的应用现状,包括检测方案、临床疗效和新技术的应用:心肌灌注、应变成像、三维超声心动图和颈动脉超声检查的辅助应用。
SE 的最新重大发现包括心肌灌注成像在多中心研究中的临床价值,以及在临床服务中与左心室(LV)壁运动评估联合应用的价值。此外,SE 在 CAD 低中度预检测概率的患者中比运动心电图更具成本效益。SE 联合颈动脉超声(CU)进行动脉粥样硬化成像,与 SE 进行缺血检测提供协同预后价值,相当于 PET-CT 混合成像。尽管出现了更新和更昂贵的成像方式,SE 仍然是 CAD 评估的基石,具有出色的临床疗效、安全性和成本效益。