Guzman-Negron Juan M, Goldman Howard B
Lerner College of Medicine, Cleveland Clinic, Glickman Urological and Kidney Institute, 9500 Euclid Ave/Q10, Cleveland, OH, 44195, USA.
Curr Urol Rep. 2017 Oct 18;18(12):94. doi: 10.1007/s11934-017-0739-y.
Overactive bladder (OAB) affects millions of people in the USA and has a significant impact on their quality of life. Despite having a number of safe and effective ways of managing refractory OAB patients, there are many promising new technologies actively being studied and developed for the treatment of this population. This review examines current new devices and technologies under study for the treatment of OAB.
Modifications to already established therapies such as sacral nerve stimulation (SNS) or tibial nerve stimulation (TNS) are currently being studied for refractory OAB. On the SNS front, a newly rechargeable, smaller neurostimulator has been developed and has shown promising results for the treatment of refractory OAB. There are two newly implantable TNS devices actively being studied for the treatment of refractory OAB. These implanted TNS systems will allow the patient to receive treatment from the comfort of their home without the need for frequent office visits. Most recently, radiofrequency ablation intravesical therapy has been proposed as a newer technology with the potential to reduce OAB symptoms. There are many new technologies actively being studied and developed for the management of refractory OAB patients. If shown to be safe and efficacious, these therapies may one day alter our current management of patients with OAB.
膀胱过度活动症（OAB）在美国影响着数百万人，对他们的生活质量有重大影响。尽管有多种安全有效的方法来管理难治性OAB患者，但仍有许多有前景的新技术正在积极研究和开发用于治疗这一人群。本综述探讨了目前正在研究用于治疗OAB的新设备和技术。
目前正在研究对已确立的疗法如骶神经刺激（SNS）或胫神经刺激（TNS）进行改进，用于治疗难治性OAB。在SNS方面，已开发出一种新的可充电、更小的神经刺激器，对难治性OAB的治疗显示出有前景的结果。有两种新的可植入TNS设备正在积极研究用于治疗难治性OAB。这些植入式TNS系统将使患者能够在家中舒适地接受治疗，而无需频繁前往诊所。最近，膀胱内射频消融疗法已被提议作为一种有潜力减轻OAB症状的新技术。有许多新技术正在积极研究和开发用于管理难治性OAB患者。如果证明安全有效，这些疗法可能有一天会改变我们目前对OAB患者的管理方式。
