Denomme Gregory A, Anani Waseem Q, Avent Neil D, Bein Gregor, Briggs Lynne B, Lapadat Razvan C, Montemayor Celina, Rios Maria, St-Louis Maryse, Uhl Lynne, Wendel Silvano, Flegel Willy A
Diagnostic Laboratories, BloodCenter of Wisconsin, 638 N 18th Street, PO Box 2178, Milwaukee, WI 53201-2178, USA.
Medical Sciences Institute, BloodCenter of Wisconsin, Milwaukee, WI, USA.
Ther Adv Hematol. 2017 Oct;8(10):277-291. doi: 10.1177/2040620717729128. Epub 2017 Sep 13.
This review summarizes the salient points of the symposium 'Red Cell Genotyping 2015: Precision Medicine' held on 10 September 2015 in the Masur Auditorium of the National Institutes of Health. The specific aims of this 6th annual symposium were to: (1) discuss how advances in molecular immunohematology are changing patient care; (2) exemplify patient care strategies by case reports (clinical vignettes); (3) review the basic molecular studies and their current implications in clinical practice; (4) identify red cell genotyping strategies to prevent alloimmunization; and (5) compare and contrast future options of red cell genotyping in precision transfusion medicine. This symposium summary captured the state of the art of red cell genotyping and its contribution to the practice of precision medicine.
本综述总结了2015年9月10日在国立卫生研究院马苏尔礼堂举行的“2015年红细胞基因分型:精准医学”研讨会的要点。第六届年度研讨会的具体目标是:(1)讨论分子免疫血液学进展如何改变患者护理;(2)通过病例报告(临床案例)举例说明患者护理策略;(3)回顾基础分子研究及其在临床实践中的当前意义;(4)确定预防同种免疫的红细胞基因分型策略;(5)比较和对比精准输血医学中红细胞基因分型的未来选择。本研讨会总结阐述了红细胞基因分型的最新技术水平及其对精准医学实践的贡献。