基于胸大肌前植入物的乳房重建术。

Prepectoral Implant-Based Breast Reconstruction.

作者信息

Highton Lyndsey, Johnson Richard, Kirwan Cliona, Murphy John

机构信息

Nightingale Breast Centre, University Hospital of South Manchester NHS Foundation Trust, United Kingdom.

出版信息

Plast Reconstr Surg Glob Open. 2017 Sep 19;5(9):e1488. doi: 10.1097/GOX.0000000000001488. eCollection 2017 Sep.

Abstract

BACKGROUND

The development of acellular dermal matrices (ADMs) has facilitated single-stage implant breast reconstruction (IBR) following skin-sparing mastectomy. The conventional approach of postpectoral implant placement with lower pole ADM confers a good cosmetic result by improving lower pole projection and control, while minimizing issues of implant visibility, palpability, and rippling. This is balanced with potential disadvantages including pain, disruption of pectoral muscle function, and animation. We report the results of a prospective study of prepectoral IBR with total ADM coverage.

METHODS

Prepectoral IBR with total ADM coverage was performed in 106 patients (166 breasts) in our institution from 2013 to 2017. The cohort included patients undergoing immediate IBR (113 breasts) and revision of existing submuscular IBR (53 breasts). Patient demographics, surgical complications, and outcomes from a prospective database were analyzed.

RESULTS

At a mean follow-up of 485 days, patient satisfaction and cosmetic outcomes have been good, with no significant capsular contractures or animation deformity. Minor complications including delayed healing, red breast, or seroma occurred in 14 breasts (8.4%). Major complications including necrosis and implant loss occurred in 5 breasts (3 patients), with a total explantation rate of 3%. No patients required more than an overnight stay in hospital, and there were no delays to adjuvant treatment in therapeutic cases.

CONCLUSION

Prepectoral implant placement with ADM cover is emerging as an alternative approach for IBR. This method facilitates breast reconstruction with a good cosmetic outcome for patients who want a quick recovery without potential compromise of pectoral muscle function and associated problems.

摘要

背景

脱细胞真皮基质(ADM)的发展推动了保乳皮肤切除术后的一期植入式乳房重建(IBR)。传统的胸后置入乳房假体并使用下极ADM的方法,通过改善下极的突出度和可控性,在最大程度减少假体可见性、可触及性和波纹问题的同时,实现了良好的美容效果。但这种方法也存在一些潜在缺点,包括疼痛、胸肌功能紊乱和动感问题。我们报告了一项对全ADM覆盖的胸前IBR进行前瞻性研究的结果。

方法

2013年至2017年,我们机构对106例患者(166侧乳房)进行了全ADM覆盖的胸前IBR。该队列包括接受即刻IBR的患者(113侧乳房)和对现有的胸肌下IBR进行修复的患者(53侧乳房)。我们分析了前瞻性数据库中的患者人口统计学资料、手术并发症及结果。

结果

平均随访485天时,患者满意度和美容效果良好,未出现明显的包膜挛缩或动感畸形。14侧乳房(8.4%)出现了包括愈合延迟、乳房发红或血清肿等轻微并发症。5侧乳房(3例患者)出现了包括坏死和假体丢失在内的严重并发症,总取出率为3%。没有患者需要住院超过一晚,治疗性病例的辅助治疗也未出现延迟。

结论

胸前植入假体并使用ADM覆盖正逐渐成为IBR的一种替代方法。对于希望快速康复且不影响胸肌功能及相关问题的患者,这种方法有助于实现乳房重建并获得良好的美容效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ae/5640360/625168cec8b2/gox-5-e1488-g001.jpg

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