Ma Wei-Xu, Chen Xin, Zhou Xing-Yu, Li Xue-Lan, Chen Wan-le, Ye De-Sheng, Chen Shi-Ling
Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. E-mail:
Nan Fang Yi Ke Da Xue Xue Bao. 2017 Oct 20;37(10):1418-1422. doi: 10.3969/j.issn.1673-4254.2017.10.24.
We report a case of ovarian function fluctuation during long-term follow-up in a patient with premature ovarian insufficiency (POI). The patient finally obtained clinical pregnancy with subsequent uneventful full-term delivery after several intracytoplasmic sperm injection-embryo transfer (ICSI-ET) cycles. This case demonstrates that hormone replacement therapy (HRT) and assisted reproductive therapy should be applied as soon as possible to young patients with POI who have a strong desire for pregnancy in the absence of contraindications. This strategy helps such patients obtain pregnancy and delivery before the exhaustion of ovarian function.
我们报告了一例卵巢早衰(POI)患者在长期随访期间卵巢功能波动的病例。该患者在经历了数个卵胞浆内单精子注射-胚胎移植(ICSI-ET)周期后最终实现临床妊娠并随后顺利足月分娩。该病例表明,对于有强烈妊娠意愿且无禁忌证的年轻POI患者,应尽早应用激素替代疗法(HRT)和辅助生殖疗法。这一策略有助于此类患者在卵巢功能耗尽之前实现妊娠和分娩。