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[卵巢早衰患者经卵胞浆内单精子注射 - 胚胎移植后成功妊娠:一例报告]

[Successful pregnancy following intracytoplasmic sperm injection?embryo transfer in a patient with premature ovarian insufficiency: a case report].

作者信息

Ma Wei-Xu, Chen Xin, Zhou Xing-Yu, Li Xue-Lan, Chen Wan-le, Ye De-Sheng, Chen Shi-Ling

机构信息

Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. E-mail:

出版信息

Nan Fang Yi Ke Da Xue Xue Bao. 2017 Oct 20;37(10):1418-1422. doi: 10.3969/j.issn.1673-4254.2017.10.24.

Abstract

We report a case of ovarian function fluctuation during long-term follow-up in a patient with premature ovarian insufficiency (POI). The patient finally obtained clinical pregnancy with subsequent uneventful full-term delivery after several intracytoplasmic sperm injection-embryo transfer (ICSI-ET) cycles. This case demonstrates that hormone replacement therapy (HRT) and assisted reproductive therapy should be applied as soon as possible to young patients with POI who have a strong desire for pregnancy in the absence of contraindications. This strategy helps such patients obtain pregnancy and delivery before the exhaustion of ovarian function.

摘要

我们报告了一例卵巢早衰(POI)患者在长期随访期间卵巢功能波动的病例。该患者在经历了数个卵胞浆内单精子注射-胚胎移植(ICSI-ET)周期后最终实现临床妊娠并随后顺利足月分娩。该病例表明,对于有强烈妊娠意愿且无禁忌证的年轻POI患者,应尽早应用激素替代疗法(HRT)和辅助生殖疗法。这一策略有助于此类患者在卵巢功能耗尽之前实现妊娠和分娩。

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本文引用的文献

1
Occult form of premature ovarian insufficiency.隐匿型卵巢早衰
Gynecol Endocrinol. 2016 Oct;32(sup2):30-32. doi: 10.1080/09513590.2016.1232676.
5
ESHRE Guideline: management of women with premature ovarian insufficiency.ESHRE 指南:卵巢早衰妇女的管理。
Hum Reprod. 2016 May;31(5):926-37. doi: 10.1093/humrep/dew027. Epub 2016 Mar 22.
7
Premature ovarian insufficiency: from pathogenesis to clinical management.卵巢早衰:从发病机制到临床管理。
J Endocrinol Invest. 2015 Jun;38(6):597-603. doi: 10.1007/s40618-014-0231-1. Epub 2015 Jan 18.
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Genetics of primary ovarian insufficiency: a review.原发性卵巢功能不全的遗传学:综述
J Assist Reprod Genet. 2014 Dec;31(12):1573-85. doi: 10.1007/s10815-014-0342-9. Epub 2014 Sep 18.
10
Premature ovarian insufficiency: how to improve reproductive outcome?卵巢早衰:如何改善生殖结局?
Climacteric. 2014 Jun;17(3):242-6. doi: 10.3109/13697137.2013.860115. Epub 2013 Dec 16.

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