Wang Huan-Jun, Guan Jian, Lin Jin-Hua, Pan Bi-Tao, Deng Chun-Hua, Guo Yan
Department of Radiology, The First Hospital Affiliated to Sun Yat-sen University, Guangzhou, Guangdong 510080, China.
Department of Ultrasonography, The First Hospital Affiliated to Sun Yat-sen University, Guangzhou, Guangdong 510080, China.
Zhonghua Nan Ke Xue. 2016 Sep;22(9):787-791.
To analyze the MRI manifestations of Peyronie's disease and investigate the value of high-field MRI in the diagnosis of the disease.
Using a small surface coil, we performed 3.0 Tesla MRI for 14 patients with clinically diagnosed Peyronie's disease. The MRI protocol included routine sequences (T1WI, T2WI, and enhanced T1WI) and susceptibility-weighted imaging (SWI). Each patient had received 2-4 penile ultrasound examinations previously. We compared the MRI findings with the results of ultrasonography.
MRI manifested 25 penile plaques in the 14 patients, 3 (7 plaques) with inflammation, 4 (8 plaques) with fibrosis, and the other 7 (10 plaques) with calcification displaying a low signal intensity on SWI. Ultrasonography had revealed the 10 calcified plaques in all the 20 examinations, but exhibited the 7 inflammatory and 8 fibrotic ones in only 3 of the 23 examinations. The combination of MRI SWI sequences was necessitated for the detection of calcified plaques and achieved higher detection rates than ultrasonography for inflammatory and fibrotic plaques (P<0.05).
High-field MRI has high sensitivity and accuracy in the diagnosis of Peyronie's disease, which can effectively display penile plaques of different nature in the early stage through multi-parametric sequences.
分析佩罗尼氏病的磁共振成像(MRI)表现,探讨高场强MRI对该病的诊断价值。
使用小表面线圈,对14例临床诊断为佩罗尼氏病的患者进行3.0特斯拉MRI检查。MRI检查方案包括常规序列(T1加权成像、T2加权成像和增强T1加权成像)和磁敏感加权成像(SWI)。每位患者此前均接受过2 - 4次阴茎超声检查。我们将MRI检查结果与超声检查结果进行比较。
14例患者的MRI显示25个阴茎硬结,其中3例(7个硬结)有炎症,4例(8个硬结)有纤维化,另外7例(10个硬结)有钙化,钙化灶在SWI上呈低信号强度。超声检查在所有20次检查中发现了10个钙化硬结,但在23次检查中仅3次发现了7个炎性和8个纤维化硬结。检测钙化硬结需要联合使用MRI的SWI序列,其对炎性和纤维化硬结的检出率高于超声检查(P<0.05)。
高场强MRI对佩罗尼氏病的诊断具有较高的敏感性和准确性,可通过多参数序列在早期有效显示不同性质的阴茎硬结。