Demiri Efterpi, Dionyssiou Dimitrios, Tsimponis Antonios, Goula Olga Christina, Mιlothridis Panagiotis, Pavlidis Leonidas, Spyropoulou Georgia Alexandra, Foroglou Perikles
Department of Plastic Surgery, Faculty of Health Sciences, School of Medicine, "Papageorgiou" Hospital, Aristotle University of Thessaloniki , Thessaloniki, Greece .
Lymphat Res Biol. 2018 Feb;16(1):2-8. doi: 10.1089/lrb.2017.0043. Epub 2017 Oct 31.
Abstracts Background: Among current surgical options used for treating breast cancer-related lymphedema (BCRL), autologous lymph node transfer (ALNT) is shown to provide favorable results. However, postoperative donor-site lymphedema (DSL), following the lymphatic flap harvesting from the groin area, has already been reported. Our aim is to summarize the recent literature for evidence of DSL following an ALNT for BCRL.
A PubMed bibliographic search was performed for published studies evaluating donor-site complications following LNT in BCRL patients. We recorded demographic data of the patients, the type of flap used, the follow-up, the donor-site morbidity, and the diagnostic tests performed pre- and postoperatively. Statistical analysis was conducted to document any correlation between the incidence of DSL and the abovementioned recorded parameters. According to our results, 11 studies met the inclusion criteria. From a total of 189 patients, three cases with DSL of the lower limb were reported (1.6%). No statistically significant correlations were found.
ALNT has become increasingly popular and is considered an effective surgical option for treating BCRL of the upper limb. Although the incidence of postoperative DSL is low, insufficient data on patients' demographics, surgical details, and postoperative assessment do not allow extracting significant correlations. Meticulous technique of lymph node harvesting should be seriously considered to further minimize this infrequent but debilitating complication.
摘要 背景：在目前用于治疗乳腺癌相关淋巴水肿（BCRL）的手术选择中，自体淋巴结转移（ALNT）显示出良好的效果。然而，已经有报道称，从腹股沟区域采集淋巴皮瓣后会出现术后供区淋巴水肿（DSL）。我们的目的是总结近期文献，以寻找ALNT治疗BCRL后发生DSL的证据。
对发表的评估BCRL患者行淋巴结转移术后供区并发症的研究进行PubMed文献检索。我们记录了患者的人口统计学数据、使用的皮瓣类型、随访情况、供区发病率以及术前和术后进行的诊断测试。进行统计分析以记录DSL发病率与上述记录参数之间的任何相关性。根据我们的结果，11项研究符合纳入标准。在总共189例患者中，报告了3例下肢DSL（1.6%）。未发现统计学上的显著相关性。
ALNT越来越受欢迎，被认为是治疗上肢BCRL的有效手术选择。尽管术后DSL的发生率较低，但关于患者人口统计学、手术细节和术后评估的数据不足，无法得出显著的相关性。应认真考虑细致的淋巴结采集技术，以进一步减少这种罕见但使人衰弱的并发症。
