Arnold-Reed Diane E, Brett Tom, Troeung Lakkhina, O'Neill Jasmine, Backhouse Rupert, Bulsara Max K
General Practice and Primary Health Care Research, School of Medicine, The University of Notre Dame Australia, Fremantle, WA, Australia.
Murray Medical Centre, Mandurah, WA, Australia.
J Comorb. 2014 Oct 6;4:46-54. doi: 10.15256/joc.2014.4.42. eCollection 2014.
Multimorbidity, the co-existence of two or more (2+) long-term conditions in an individual, is common among problem drug abusers.
To delineate the patterns, multimorbidity prevalence, and disease severity in patients enrolled in a community-based primary care methadone maintenance treatment (MMT) programme.
This was a retrospective cohort study (=274). The comparator group consisted of mainstream primary care patients. Electronic medical record assessment was performed using the Cumulative Illness Rating Scale.
Prevalence of multimorbidity across 2+ domains was significantly higher within the MMT sample at 88.7% (243/274) than the comparator sample at 51.8% (142/274), <0.001. MMT patients were seven times more likely to have multimorbidity across 2+ domains compared with mainstream patients (OR 7.29, 95% confidence interval 4.68-11.34; <0.001). Prevalence of multimorbidity was consistently high across all age groups in the MMT cohort (range 87.8-100%), while there was a positive correlation with age in the comparator cohort (=0.29, <0.001). Respiratory, psychiatric, and hepatic-pancreatic domains were the three most common domains with multimorbidity. Overall, MMT patients (mean±SD, 1.97±0.43) demonstrated significantly higher disease severity than mainstream patients (mean±SD, 1.18±0.78), 0.001. Prevalence of moderate disease severity observed in the <45-year MMT age group was 50% higher than the ≥45-year comparator age group.
Prevalence of multimorbidity and disease severity in MMT patients was greater than in the age- and sex-matched comparators. Patients with a history of drug abuse require co-ordinated care for treatment of their addiction, and to manage and prevent chronic illnesses. Community-based programmes delivered through primary care help fulfil this need.
多重疾病指个体同时存在两种或更多种长期病症,在问题药物滥用者中很常见。
描述参与社区基层美沙酮维持治疗(MMT)项目患者的疾病模式、多重疾病患病率及疾病严重程度。
这是一项回顾性队列研究(n = 274)。对照组由基层主流医疗患者组成。使用累积疾病评定量表进行电子病历评估。
MMT样本中两种及以上领域的多重疾病患病率显著高于对照组,分别为88.7%(243/274)和51.8%(142/274),P < 0.001。与主流患者相比,MMT患者出现两种及以上领域多重疾病的可能性高出7倍(比值比7.29,95%置信区间4.68 - 11.34;P < 0.001)。MMT队列中所有年龄组的多重疾病患病率始终很高(范围87.8 - 100%),而对照组中患病率与年龄呈正相关(r = 0.29,P < 0.001)。呼吸、精神和肝胰领域是多重疾病最常见的三个领域。总体而言,MMT患者(均值±标准差,1.97±0.43)的疾病严重程度显著高于主流患者(均值±标准差,1.18±0.78),P = 0.001。在年龄小于45岁的MMT年龄组中观察到的中度疾病严重程度患病率比年龄大于等于45岁的对照组年龄组高50%。
MMT患者的多重疾病患病率和疾病严重程度高于年龄及性别匹配的对照组。有药物滥用史的患者需要协调护理以治疗成瘾问题,并管理和预防慢性病。通过基层医疗提供的社区项目有助于满足这一需求。