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阻塞性睡眠呼吸暂停患者的弗里德曼舌位与锥形束计算机断层扫描

Friedman tongue position and cone beam computed tomography in patients with obstructive sleep apnea.

作者信息

Harvey Rebecca, O'Brien Louise, Aronovich Sharon, Shelgikar Anita, Hoff Paul, Palmisano John, Stanley Jeffrey

机构信息

Department of Otolaryngology Michigan U.S.A.

Department of Sleep Medicine Michigan U.S.A.

出版信息

Laryngoscope Investig Otolaryngol. 2017 Aug 22;2(5):320-324. doi: 10.1002/lio2.92. eCollection 2017 Oct.

DOI:10.1002/lio2.92
PMID:29094076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5655544/
Abstract

OBJECTIVE

Evaluate the correlation between Friedman Tongue Position (FTP) and airway cephalometrics in patients with obstructive sleep apnea (OSA).

STUDY DESIGN

Retrospective review of adult patients with OSA undergoing Cone Beam Computed Tomography (CBCT).

METHODS

Collected data included age, sex, body mass index, apnea hypopnea index, FTP, and airway cephalometric parameters. Data analyses were performed using ANOVA, dichotomous t-testing, and linear regression.

RESULTS

203 patients were included in the analysis. (M:F 132:71). The mean posterior airway space (PAS) was inversely correlated ( = 0.001, =.119) with higher FTP grades with means of 12.3 mm, 7.9 mm, 6.6 mm, and 4.3 mm, I-IV respectively. Minimal cross-sectional area for patients with FTP I-IV was 245.7, 179.8, 137.6, and 74.2 mm, 2 respectively ( = 0.002,  = .095). Mean hyoid-mandibular plane (H-MP) for FTP I-IV was 20.6 mm, 20.4 mm, 24.7 mm, and 28.9 mm respectively. No statistically significant difference between H-MP values when comparing patients with FTP I or II ( = 0.22). There were statistically significant differences when these two groups were individually compared to FTP III and IV ( = 0.002). Linear regression analysis confirmed an independent association between FTP and PAS (β = -2.06,  < 0.001), minimal cross-sectional area (β = -45.07,  = 0.02), and H-MP (β = 3.03,  = 0.01) controlling for BMI, age, AHI, and sex.

CONCLUSIONS

Use of FTP is supported by objective CBCT cephalometric results, in particular the PAS, minimal cross-sectional area, and H-MP. Understanding the correlation between objective measurements of retroglossal collapse should allow Otolaryngologists to more confidently select patients who may require surgery to address the retroglossal area, particularly when the ability to perform cephalometric analysis is not possible.

LEVEL OF EVIDENCE

摘要

目的

评估阻塞性睡眠呼吸暂停(OSA)患者的弗里德曼舌位(FTP)与气道头影测量之间的相关性。

研究设计

对接受锥形束计算机断层扫描(CBCT)的成年OSA患者进行回顾性研究。

方法

收集的数据包括年龄、性别、体重指数、呼吸暂停低通气指数、FTP和气道头影测量参数。使用方差分析、二分t检验和线性回归进行数据分析。

结果

203例患者纳入分析(男∶女=132∶71)。平均后气道间隙(PAS)与较高的FTP分级呈负相关(P=0.001,r=-0.119),I-IV级的平均值分别为12.3mm、7.9mm、6.6mm和4.3mm。FTP I-IV级患者的最小横截面积分别为245.7、179.8、137.6和74.2mm²(P=0.002,r=-0.095)。FTP I-IV级的平均舌骨-下颌平面(H-MP)分别为20.6mm、20.4mm、24.7mm和28.9mm。比较FTP I或II级患者时,H-MP值之间无统计学显著差异(P=0.22)。将这两组分别与FTP III和IV级比较时,有统计学显著差异(P=0.002)。线性回归分析证实,在控制体重指数、年龄、呼吸暂停低通气指数和性别后,FTP与PAS(β=-2.06,P<0.001)、最小横截面积(β=-45.07,P=0.02)和H-MP(β=3.03,P=0.01)之间存在独立关联。

结论

客观的CBCT头影测量结果,特别是PAS、最小横截面积和H-MP,支持使用FTP。了解舌后塌陷客观测量之间的相关性应使耳鼻喉科医生能够更自信地选择可能需要手术治疗舌后区域的患者,尤其是在无法进行头影测量分析的情况下。

证据级别

4级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/038a/5655544/6acbaf0ada92/LIO2-2-320-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/038a/5655544/0a38d6e35fa8/LIO2-2-320-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/038a/5655544/6acbaf0ada92/LIO2-2-320-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/038a/5655544/0a38d6e35fa8/LIO2-2-320-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/038a/5655544/6acbaf0ada92/LIO2-2-320-g002.jpg