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腹部手术后长期预后的前瞻性研究。

Prospective study on long-term outcome after abdominal surgery.

作者信息

Brynjarsdottir E D, Sigurdsson M I, Sigmundsdottir E, Möller P H, Sigurdsson G H

机构信息

Department of Internal Medicine, Landspitali - The National University Hospital of Iceland, Reykjavik, Iceland.

Faculty of Medicine, University of Iceland, Reykjavik, Iceland.

出版信息

Acta Anaesthesiol Scand. 2018 Feb;62(2):147-158. doi: 10.1111/aas.13025. Epub 2017 Nov 1.

Abstract

BACKGROUND

Complications following major abdominal surgery are common and an important cause of morbidity and mortality. The aim of this study was to describe 1-year mortality and identify factors that influence adverse outcomes after abdominal surgery.

METHODS

This prospective observational cohort study was performed in Landspitali University Hospital and included all adult patients undergoing abdominal surgery requiring > 24-h hospital admission over 13 months. The follow-up period was 60 days for complications and 24 months for mortality.

RESULTS

Data were available for 1113 (99.5%) of the 1119 patients who fulfilled inclusion criteria. A total of 23% of patients had at least one underlying co-morbidity. Non-elective surgeries were 48% and 13% of the patients were admitted to ICU post-operatively. A total of 20% of patients developed complications. Mortality at 30 days, 1 and 2 years was 1.8%, 5.6%, and 8.3% respectively. One-year mortality for those admitted to ICU was 18%. The long-term survival of the individuals surviving 30 days was significantly worse than for an age- and gender-matched population control group. Independent predictors for 1-year mortality were age, pre-operative acute kidney injury and intermediate- or major surgery.

CONCLUSION

Post-operative complication rates and mortality following abdominal surgery in Iceland were comparable or in the lower range of previously published outcomes, validating the utility of offering a full host of abdominal surgical services in geographically isolated region with a relatively small referral base.

摘要

背景

腹部大手术后的并发症很常见,是发病和死亡的重要原因。本研究的目的是描述1年死亡率,并确定影响腹部手术后不良结局的因素。

方法

这项前瞻性观察性队列研究在冰岛国家大学医院进行,纳入了所有在13个月内接受需要住院超过24小时的腹部手术的成年患者。并发症的随访期为60天,死亡率的随访期为24个月。

结果

1119例符合纳入标准的患者中,1113例(99.5%)有可用数据。共有23%的患者至少有一种基础合并症。非择期手术占48%,13%的患者术后入住重症监护病房。共有20%的患者发生并发症。30天、1年和2年的死亡率分别为1.8%、5.6%和8.3%。入住重症监护病房患者的1年死亡率为18%。存活30天的患者的长期生存率明显低于年龄和性别匹配的人群对照组。1年死亡率的独立预测因素是年龄、术前急性肾损伤以及中大型手术。

结论

冰岛腹部手术后的术后并发症发生率和死亡率与之前公布的结果相当或处于较低水平,这证实了在转诊基数相对较小的地理孤立地区提供全面腹部手术服务的实用性。

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