Mangin L, Lotfi M, Puie P, Yayehd K, Ispas A, Belle L
Service de cardiologie, centre hospitalier, 74000 Annecy, France.
Service de cardiologie, centre hospitalier, 74000 Annecy, France.
Ann Cardiol Angeiol (Paris). 2017 Dec;66(6):380-384. doi: 10.1016/j.ancard.2017.10.016. Epub 2017 Oct 31.
A large thrombus burden is not uncommon in primary percutaneous coronary intervention, and is associated with more frequent complications. The role of intracoronary thrombolysis and glycoprotein IIb/IIIa inhibitors in the management of a large thrombus burden is discussed. The use of thromboaspiration must follow a particular logic and used with rigorous manipulations; the capacities of the protective filters are often exceeded. Stents dedicated to thrombus management can be used. Interest and limits of these stents are developed. Direct stenting should be encouraged, and delayed stenting probably considered for the most important thrombotic burden despite "negative" results in studies.
在直接经皮冠状动脉介入治疗中,大量血栓负荷并不少见,且与更频繁的并发症相关。本文讨论了冠状动脉内溶栓和糖蛋白IIb/IIIa抑制剂在处理大量血栓负荷中的作用。血栓抽吸的使用必须遵循特定逻辑并严格操作;保护滤网的容量常常会被超出。可使用专门用于处理血栓的支架。本文阐述了这些支架的优势和局限性。应鼓励直接支架置入,尽管相关研究结果为“阴性”,但对于血栓负荷最重的情况可能仍需考虑延迟支架置入。