Joint Replacement Centre, Army Hospital Research & Referral, New Delhi, India.
Department of Orthopaedics, KIMS Medical College, Bhubaneswar, India.
J Arthroplasty. 2018 Mar;33(3):752-760. doi: 10.1016/j.arth.2017.09.068. Epub 2017 Oct 10.
Simultaneous bilateral total knee arthroplasty (SBTKA) offers significant socioeconomic benefits. However, retrospective studies and public health data show increased mortality and morbidity rates in patients undergoing SBTKA compared with those undergoing unilateral TKA (UTKA), and there have been recommendations against the use of SBTKA. High-volume centers, which feature careful patient selection and fast-tracked surgery, continue to perform SBTKA and have published their results in favor of the procedure. However, the quality of evidence remains poor.
We prospectively examined 90-day morbidity and mortality of SBTKA compared with UTKA in risk-screened and optimized patients in our high-volume joint replacement facility. A total of 1200 consecutive patients were recruited in each arm.
Ninety-day mortality was higher in SBTKA patients than in UTKA patients (0.58% vs 0.42%, respectively; P = .5646). Overall procedure-related complications were significantly higher in the SBTKA group (7.25% vs 4.42%, respectively; P = .0034). The relative risk of cardiovascular complications in SBTKA patients was 6.5 times higher than that in UTKA patients (1.08% vs 0.17%, respectively; P = .0136). Neurological complications were 9.5 times more common in the SBTKA group (1.58% vs 0.17%, respectively; P = .0024). All other complications were comparable in the 2 groups.
Risk screening and preoperative optimization reduce mortality and overall complication rates in SBTKA patients; however, overall procedure-related complications, specifically cardiovascular and neurological, remain significantly high in SBTKA patients, for which a guarded approach is recommended.
同期双侧全膝关节置换术(SBTKA)具有显著的社会效益。然而,回顾性研究和公共卫生数据显示,与单侧全膝关节置换术(UTKA)相比,SBTKA 患者的死亡率和发病率更高,并且有建议反对使用 SBTKA。高容量中心,其特点是精心挑选患者和快速手术,继续进行 SBTKA,并发表了支持该手术的结果。然而,证据质量仍然很差。
我们前瞻性地检查了我们高容量关节置换设施中风险筛查和优化后的 SBTKA 与 UTKA 患者的 90 天发病率和死亡率。每个臂招募了 1200 例连续患者。
SBTKA 患者的 90 天死亡率高于 UTKA 患者(分别为 0.58%和 0.42%;P=.5646)。SBTKA 组的总体手术相关并发症明显高于 UTKA 组(分别为 7.25%和 4.42%;P=.0034)。SBTKA 患者心血管并发症的相对风险是 UTKA 患者的 6.5 倍(分别为 1.08%和 0.17%;P=.0136)。SBTKA 组的神经系统并发症更为常见(分别为 1.58%和 0.17%;P=.0024)。两组其他并发症相当。
风险筛查和术前优化可降低 SBTKA 患者的死亡率和总体并发症发生率;然而,SBTKA 患者的总体手术相关并发症,特别是心血管和神经系统并发症仍然很高,建议采取谨慎的方法。