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Meckel's 憩室出血:锝扫描作为诊断工具的准确性研究。

Bleeding meckel's diverticulum: A study of the accuracy of pertechnetate scintigraphy as a diagnostic tool.

机构信息

Department of Radiology, Our Lady's Hospital for Sick Children, Crumlin, Dublin 12, Ireland.

出版信息

Eur J Radiol. 2017 Nov;96:27-30. doi: 10.1016/j.ejrad.2017.09.008. Epub 2017 Sep 14.

Abstract

BACKGROUND

The reported accuracy of pertechnetate scintigraphy (Meckel scan) in investigating children with a bleeding Meckel's diverticulum has increased steadily since it was first introduced into clinical practice in 1970. Recent studies have indicated that the examination has a sensitivity of up to 94% and a specificity of up to 97% in this scenario. There have also been several misleading reviews from Departments of Surgery, suggesting that the Meckel scan has a poor predictive value, and should not be relied upon to exclude a bleeding Meckel's Diverticulum (MD).

OBJECTIVE

The aim of this study was to assess the accuracy of pertechnetate scintigraphy performed at Our Lady's Hospital for Sick Children, Crumlin (OLCHC) on children with clinical suspicion of a bleeding MD.

METHOD

This was a retrospective study of all the Meckel scans performed over a 10year period (2005-2015) in OLCHC, 144 in total.

RESULTS

Of the total 144 scans performed, 22 were considered to be positive, and all patients were found to have a MD at surgery. 122 were negative, and in 53 of these patients, an alternative cause for symptoms was found, often at endoscopy. In the remaining 69 patients, no cause was found, despite full medical work-up. In all of these cases, symptoms resolved, and have not yet recurred, making MD very unlikely.

DISCUSSION

Pertechnetate scintigraphy, when performed using meticulous technique, can provide up to 100% sensitivity CI [85.1, 100.0] and 100% specificity CI [93.2, 100.0] in diagnosing a bleeding MD in a paediatric population. This examination is seldom of value in children with no history of rectal bleeding.

摘要

背景

自 1970 年首次将放射性锝扫描( Meckel 扫描)引入临床实践以来,其诊断有出血性 Meckel 憩室的准确性一直在稳步提高。最近的研究表明,在这种情况下,该检查的敏感性高达 94%,特异性高达 97%。也有来自外科部门的一些误导性综述表明, Meckel 扫描的预测值较差,不应依赖它来排除有出血性 Meckel 憩室(MD)的情况。

目的

本研究旨在评估 Our Lady's Hospital for Sick Children,Crumlin(OLCHC)对有临床怀疑有出血性 MD 的儿童进行放射性锝扫描的准确性。

方法

这是一项对 OLCHC 在 10 年内(2005-2015 年)进行的所有 Meckel 扫描的回顾性研究,共 144 例。

结果

在总共进行的 144 次扫描中,有 22 次被认为是阳性的,所有患者在手术中均发现有 MD。122 次为阴性,在其中 53 例患者中,症状的替代原因在进行内镜检查时发现。在其余 69 例患者中,尽管进行了全面的医学检查,但仍未找到病因。在所有这些情况下,症状都得到缓解,并且尚未再次出现,这使得 MD 非常不可能。

讨论

当使用细致的技术进行锝扫描时,在儿科人群中,它可以提供高达 100%的敏感性 CI [85.1, 100.0] 和 100%的特异性 CI [93.2, 100.0],用于诊断有出血性 MD 的情况。对于没有直肠出血病史的儿童,该检查很少有价值。

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