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妊娠期糖尿病——饮食和胰岛素是唯一的解决办法吗?

Gestational diabetes - is diet and insulin the only solution?

作者信息

Brzozowska Maria, Bieniek Ewa, Szosland Konrad, Lewinski Andrzej

机构信息

Department of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital and Research Institute, Lodz, Poland.

出版信息

Neuro Endocrinol Lett. 2017 Oct;38(5):311-315.

Abstract

Gestational diabetes (GDM) is a relatively common complication of pregnancy. Maternal hyperglycemia causes many serious side effects for mothers, fetuses and newborns. In 90% of women diagnosed with GDM, a dietary treatment results in satisfactory levels of blood glucose. The remaining 10% require insulin therapy to achieve the recommended glycemic levels. The majority of recent studies show the efficiency of metformin in gestational diabetes and prove that it is not a cause for any harmful side effects to the embryo and/or fetus. Metformin is an effective alternative to insulin in glycemic control in pregnant women. The implementation of metformin, as a routine procedure in gestational diabetes, requires further research, the results of which would unequivocally confirm its efficacy and safety for pregnant women and their offspring.

摘要

妊娠期糖尿病(GDM)是一种相对常见的妊娠并发症。母体高血糖会给母亲、胎儿和新生儿带来许多严重的副作用。在90%被诊断为GDM的女性中,饮食治疗可使血糖水平达到满意状态。其余10%的患者需要胰岛素治疗以达到推荐的血糖水平。最近的大多数研究表明二甲双胍对妊娠期糖尿病有效,并证明它不会对胚胎和/或胎儿造成任何有害副作用。在控制孕妇血糖方面,二甲双胍是胰岛素的有效替代品。将二甲双胍作为妊娠期糖尿病的常规治疗方法,还需要进一步研究,其结果将明确证实其对孕妇及其后代的有效性和安全性。

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