Centre for Applied Health Economics & Menzies Health Institute Queensland, Griffith University, Brisbane, Australia.
QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Am J Med. 2018 Apr;131(4):415-421.e1. doi: 10.1016/j.amjmed.2017.10.019. Epub 2017 Dec 11.
The Coaching On Achieving Cardiovascular Health (COACH) Program has been proven to improve biomedical and lifestyle cardiovascular disease (CVD) risk factors. The objective of this study was to evaluate the long-term impact of The COACH Program on overall survival, hospital utilization, and costs from the perspective of a private health insurer (payor), in patients with CVD.
A prospective parallel-group case-control study design with controls randomly matched to patients based on propensity score. There were 512 participants with CVD engaged in a structured disease management program of 6 months duration (The COACH Program) who were matched to 512 patients with CVD who were allocated to the control group. The independent variables that estimated the propensity score were preprogram hospital admissions, age, and sex. The primary outcome was overall survival with secondary outcomes, including hospital utilization and cost incurred by the private health insurer. Mean follow-up was 6.35 years. Difference in overall survival between the 2 groups was estimated using a Cox proportional hazard ratio (HR) with difference in total cost estimated using a generalized linear model.
The COACH Program achieved a significant reduction in overall mortality (HR 0.70; 95% confidence interval [CI], 0.53-0.93; P = .014). There was an apparent dose-response effect: those who received up to 3 coaching sessions had no decrease in mortality (HR 1.02; 95% CI, 0.69-1.49; P = .926); those who received 4 or more coaching sessions had a substantial decrease in mortality (HR 0.58; 95% CI, 0.42-0.81; P = .001). Total cost to the health insurer was substantially lower in the intervention group ($12,707 per person lower; P = .078). The reduction in total cost was significantly greater in those who received 4 or more sessions ($19,418 per person; P = .006) and in males ($18,947 per person; P = .029).
Those enrolled in The COACH program achieved a statistically significant decrease in overall mortality compared with usual care at 6.35 years. A substantive reduction in hospital costs was also observed among those who received The COACH program compared with those who did not, particularly in those who received 4 or more sessions and in males.
教练在实现心血管健康(COACH)计划已被证明可以改善生物医学和生活方式心血管疾病(CVD)的风险因素。本研究的目的是从私人健康保险公司(支付方)的角度评估 COACH 计划对整体生存率、医院利用和成本的长期影响,对象为 CVD 患者。
采用前瞻性平行组病例对照研究设计,对照组根据倾向评分随机匹配患者。512 名 CVD 患者参加了为期 6 个月的结构化疾病管理计划(COACH 计划),与 512 名被分配到对照组的 CVD 患者相匹配。估计倾向评分的自变量包括预方案住院、年龄和性别。主要结局是整体生存率,次要结局包括医院利用率和私人健康保险公司的成本。平均随访 6.35 年。使用 Cox 比例风险比(HR)估计两组之间的整体生存率差异,使用广义线性模型估计总成本差异。
COACH 计划显著降低了总死亡率(HR 0.70;95%置信区间 [CI],0.53-0.93;P =.014)。存在明显的剂量反应效应:接受多达 3 次辅导的患者死亡率没有下降(HR 1.02;95%CI,0.69-1.49;P =.926);接受 4 次或更多辅导的患者死亡率显著下降(HR 0.58;95%CI,0.42-0.81;P =.001)。干预组对保险公司的总成本显著降低(每人降低 12707 美元;P =.078)。接受 4 次或更多辅导的患者(每人降低 19418 美元;P =.006)和男性(每人降低 18947 美元;P =.029)的总成本降低幅度明显更大。
与常规护理相比,参加 COACH 计划的患者在 6.35 年内总体死亡率显著下降。与未参加 COACH 计划的患者相比,接受 COACH 计划的患者的医院成本也显著降低,尤其是接受 4 次或更多辅导的患者和男性。