万古霉素类过敏样反应：一例报告

Anaphylactoid reaction to vancomycin: report of a case.

作者信息

Roelofse J A, Joubert J J

机构信息

Faculty of Dentistry, University of Stellenbosch, Cape Town, Republic of South Africa.

出版信息

J Oral Maxillofac Surg. 1989 Jan;47(1):69-71. doi: 10.1016/0278-2391(89)90128-6.

DOI:10.1016/0278-2391(89)90128-6

PMID:2911059

Abstract

Although vancomycin produces excellent prophylaxis against staphylococci, the danger of hypotension, whether secondary to anaphylactoid response or myocardial depression, exists. Therefore, recommendation for the use of vancomycin before dental procedures must include the precaution of administration in a dilute solution over 30 minutes, with frequent monitoring of BP and heart rate.

摘要

尽管万古霉素对葡萄球菌有很好的预防作用，但存在低血压风险，无论是继发于类过敏反应还是心肌抑制。因此，在牙科手术前使用万古霉素的建议必须包括在30分钟内用稀释溶液给药的预防措施，并频繁监测血压和心率。