Department of Hepato-Pancreato-Biliary Surgery & Liver Transplantation, Royal Free Hospital, London, UK.
Pancreatic Surgery Unit, Pancreas Translational & Research Institute, Scientific Institute San Raffaele Hospital & University "Vita e Salute", Milan, Italy.
Eur J Surg Oncol. 2019 Jan;45(1):46-51. doi: 10.1016/j.ejso.2017.08.019. Epub 2017 Oct 16.
Pancreatic Neuroendocrine Neoplasms comprise a group of rare tumours with special biology, an often indolent behaviour and particular diagnostic and therapeutic requirements. The specialized biochemical tests and radiological investigations, the complexity of surgical options and the variety of medical treatments that require individual tailoring, mandate a multidisciplinary approach that can be optimally achieved through an organized network. The present study describes currents concepts in the management of these tumours as well as an insight into the challenges of delivering the pathway in and outside a Network.
胰腺神经内分泌肿瘤是一组罕见的肿瘤,具有特殊的生物学特性、较为惰性的行为以及特殊的诊断和治疗需求。这些肿瘤需要专门的生化检测和影像学检查、复杂的手术选择以及个体化定制的多种治疗方法,这就要求采用多学科的方法,而通过有组织的网络可以实现这一方法的最优化。本研究描述了这些肿瘤的当前管理理念,以及在网络内外提供该治疗路径所面临的挑战。