头颈部癌的正电子发射断层扫描-计算机断层扫描：当前证据与未来方向

PET-Computed Tomography in Head and Neck Cancer: Current Evidence and Future Directions.

作者信息

Chen Yin Jie, Rath Tanya, Mohan Suyash

机构信息

Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Hospital of the University of Pennsylvania, 1 Silverstein, 3400 Spruce Street, Philadelphia, PA 19104, USA.

Departments of Radiology and Otolaryngology, University of Pittsburgh School of Medicine, Radiology Administration, PUH Suite E204, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

出版信息

Magn Reson Imaging Clin N Am. 2018 Feb;26(1):37-49. doi: 10.1016/j.mric.2017.08.003. Epub 2017 Oct 12.

DOI:10.1016/j.mric.2017.08.003

PMID:29128005

Abstract

Head and neck cancers are among the most common cancers worldwide. More than 90% to 95% are squamous cell carcinomas (SCCs). Accurate staging at diagnosis optimizes treatment planning with improved outcomes. Recently, 18F-fluorodeoxyglucose (FDG) PET-computed tomography (CT) has shown tremendous value at diagnosis for accurate staging, treatment planning, and prognostication; and after definitive therapy for assessing response and long-term surveillance. Novel non-FDG PET tracers are under investigation, which have great potential for improving patient care in this era of personalized medicine.

摘要

头颈癌是全球最常见的癌症之一。超过90%至95%为鳞状细胞癌（SCC）。诊断时的准确分期可优化治疗方案并改善预后。最近，18F-氟脱氧葡萄糖（FDG）正电子发射断层扫描-计算机断层扫描（PET-CT）在诊断、准确分期、治疗规划和预后评估方面显示出巨大价值；在确定性治疗后，可用于评估反应和长期监测。新型非FDG PET示踪剂正在研究中，在这个个性化医疗时代，它们在改善患者护理方面具有巨大潜力。