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基于短信的维持干预对住院认知行为治疗后重度抑郁症的评价。

Evaluation of a text-message-based maintenance intervention for Major Depressive Disorder after inpatient cognitive behavioral therapy.

机构信息

Friedrich-Alexander University Erlangen-Nuernberg, Germany; Philipps-University Marburg, Germany.

Friedrich-Alexander University Erlangen-Nuernberg, Germany.

出版信息

J Affect Disord. 2018 Feb;227:305-312. doi: 10.1016/j.jad.2017.10.047. Epub 2017 Oct 29.

Abstract

INTRODUCTION

High relapse rates in Major Depressive Disorder (MDD) indicate the need for interventions enhancing the sustainability of treatment outcomes. Primary aim of the present study was to evaluate the effectiveness of a text-message-based maintenance intervention for depression (TMMI-D). Additionally, we aimed to clarify whether the use of individualized messages would lead to better outcome than the use of standardized messages which focused upon adaptive ways of regulating undesired emotions.

METHODS

In this RCT, 226 individuals who had completed inpatient treatment for MDD were randomly allocated to a condition in which participants received TMMI-D with standardized messages targeting emotion regulation, or to a condition with individualized messages, or to a waitlist control condition. Primary outcome was depressive symptom severity assessed with the BDI-II.

RESULTS

Multilevel analyses suggest that participants receiving TIMMI-D with standardized messages reported a significantly smaller increase of depressive symptoms during the post-treatment and follow-up interval than did patients in the waitlist control condition. Contrastingly, there was no such effect for patients who had used TIMMI-D with individualized messages.

LIMITATIONS

Limitations include proportions of missing data, thus, generalizing the findings of the present study might be an overestimation.

CONCLUSION

Text-message-based interventions may help increase the sustainability of outcome after treatment for MDD. The unexpected superiority of the standardized over the individualized version is in line with research that points to the efficacy of interventions fostering adaptive emotion regulation as a means to treat depression (and other mental disorders).

摘要

介绍

重度抑郁症(MDD)的高复发率表明需要干预措施来提高治疗效果的可持续性。本研究的主要目的是评估基于短信的抑郁症维持干预(TMMI-D)的有效性。此外,我们旨在澄清使用个性化消息是否会比使用专注于调节不良情绪的适应性方法的标准化消息导致更好的结果。

方法

在这项 RCT 中,226 名完成 MDD 住院治疗的个体被随机分配到以下条件之一:接受 TMMI-D 与针对情绪调节的标准化消息,或接受个性化消息,或接受候补名单对照条件。主要结果是使用 BDI-II 评估的抑郁症状严重程度。

结果

多层次分析表明,与候补名单对照条件的患者相比,接受 TMMI-D 与标准化消息的患者在治疗后和随访期间报告的抑郁症状增加显著较小。相反,使用 TMMI-D 与个性化消息的患者则没有这种效果。

局限性

限制包括缺失数据的比例,因此,对本研究结果的推广可能会过高估计。

结论

基于短信的干预措施可能有助于提高 MDD 治疗后结果的可持续性。标准化版本优于个性化版本的意外优势与研究一致,该研究指出促进适应性情绪调节的干预措施作为治疗抑郁症(和其他精神障碍)的一种手段的有效性。

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