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[体外冲击波碎石术治疗近端输尿管结石的疗效]

[The effiectiveness of extracorporeal shock wave lithotripsy in treating proxima ureteral stones].

作者信息

Kogan M I, Belousov I I, Yassine A M

机构信息

Department of Urology and Human Reproductive Health with the Course of Pediatric Urology-Andrology, Faculty of AT and PRS, Rostov Stata Medical University of Minzdrav of Russia, Rostov on Don, Russia.

NMC Specialty Hospital, Dubai, United Arab Emirates.

出版信息

Urologiia. 2017 Oct(5):5-8. doi: 10.18565/urology.2017.5.5-8.

Abstract

UNLABELLED

Extracorporeal shock wave lithotripsy (ESWL) has proven efficacy in the treatment of proximal ureteral stones. The research to date has not been able to establish real time to spontaneous stone clearance after ESWL and the appropriateness and effectiveness of -blockers in stimulating residual stone clearance after ESWL.

AIM

To conduct a comprehensive assessment of the effectiveness of ESWL in treating proximal ureteral stones and determine the appropriateness of using -blockers to stimulate residual stone clearance.

MATERIALS AND METHODS

ESWL was performed in 40 patients with X-ray positive proximal ureteral stones. Before ESWL and at 3 months after the treatment all patients underwent multispiral computed tomography. ESWL was considered successful if there was a complete clearance of the stones with no residual fragments on the control MSCT. If a residual ureteral stone was found at 3 months after ESWL, a 2-week course of silodosin was administered.

RESULTS

Complete stone clearance was achieved in 37.5% of patients. Silodosin therapy for residual stones resulted in stone clearance in 68.4% of cases. Taken together, ESWL monotherapy and additional 3 months of lithokinetic therapy resulted in stone clearance in 70.0% of patients. The remaining patients underwent contact ureteral lithotripsy.

CONCLUSION

Spontaneous stone passage after ESWL for proximal ureteral stones occurs not in all patients. Most commonly it occurred during the first three weeks after ESWL, and thereafter stone passage was not observed. In half of the patients with residual stones they were asymptomatic. The effectiveness of ESWL as a monotherapy for ureteral stones greater than 15 mm is incomplete. Adding silodosin during the long-term post ESWL period improves the passage of asymptomatic residual stones in 2/3 of patients, which makes its use promising.

摘要

未标注

体外冲击波碎石术(ESWL)已被证明对治疗近端输尿管结石有效。迄今为止的研究未能确定ESWL后结石自然排出的实时情况以及β受体阻滞剂在促进ESWL后残余结石排出方面的适用性和有效性。

目的

全面评估ESWL治疗近端输尿管结石的有效性,并确定使用β受体阻滞剂促进残余结石排出的适用性。

材料与方法

对40例X线阳性近端输尿管结石患者进行ESWL治疗。在ESWL治疗前及治疗后3个月,所有患者均接受多层螺旋计算机断层扫描。如果在对照MSCT上结石完全清除且无残余碎片,则认为ESWL治疗成功。如果在ESWL治疗后3个月发现残余输尿管结石,则给予2周的西洛多辛疗程。

结果

37.5%的患者实现了结石完全清除。西洛多辛治疗残余结石使68.4%的病例实现了结石清除。总体而言,ESWL单一疗法及额外3个月的促排石治疗使70.0%的患者实现了结石清除。其余患者接受了输尿管接触碎石术。

结论

ESWL治疗近端输尿管结石后并非所有患者都会出现结石自然排出。最常见的情况是在ESWL后的前三周内发生,此后未观察到结石排出。一半有残余结石的患者无症状。ESWL作为大于15mm输尿管结石的单一疗法效果不完全。在ESWL后的长期阶段添加西洛多辛可使2/3的患者无症状残余结石排出情况得到改善,这使其应用前景广阔。

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